From the Division of Surgical Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Boston, MA.
J Am Coll Surg. 2023 Jun 1;236(6):1172-1179. doi: 10.1097/XCS.0000000000000560. Epub 2023 Jan 12.
The authors aimed to assess the safety of an enhanced recovery after surgery (ERAS) and early discharge pathway in a robotic pancreatoduodenectomy (PD) program and compared outcomes with an open PD control cohort to identify the synergistic effects of robotic surgery and an ERAS pathway on lengths of stay (LOS).
Consecutive patients undergoing open or robotic PD from a single surgeon between March 2020 and July 2022 were identified. Logistic regression models were used for adjusted analyses of postoperative outcomes.
There were 134 consecutive PD patients, of which 40 (30%) were performed robotically. Pancreatic adenocarcinoma was the most common indication in both open (56%) and robotic (55%, p = 0.51) groups, with a similar proportion of them being borderline resectable or locally advanced tumors (78% vs 82% in robotic group, p = 0.82). The LOS was significantly shorter in the robotic PD group (median, 5 [IQR 4 to 7] days) when compared with the open PD group (median, 6 [IQR 5 to 8] days, p < 0.001). LOS of 4 days or fewer were observed in 40% of the robotic PD group compared with only 3% of patients in the open PD group (p < 0.001). There was no difference in the overall readmission rate (10% vs 12% in the robotic PD group, p = 0.61). On multivariable logistic regression, robotic PD was independently associated with higher odds of LOS of 4 days or fewer (odds ratio 22.4, p = 0.001) when compared with open PD.
An ERAS and early discharge pathway could be safely implemented in a robotic PD program. Patients undergoing robotic PD have significantly shorter length of stay without increased complication or readmission rate compared with open PD, with 40% of patients undergoing robotic PD achieving a LOS of 4 days or fewer.
作者旨在评估机器人胰十二指肠切除术(PD)程序中手术后恢复增强(ERAS)和早期出院途径的安全性,并将其与开放 PD 对照组的结果进行比较,以确定机器人手术和 ERAS 途径对住院时间(LOS)的协同作用。
从一位外科医生在 2020 年 3 月至 2022 年 7 月期间进行的连续 PD 患者中确定了接受开放或机器人 PD 的患者。使用逻辑回归模型对术后结果进行调整分析。
共有 134 例连续 PD 患者,其中 40 例(30%)采用机器人手术。开放(56%)和机器人(55%,p=0.51)组中最常见的适应症均为胰腺腺癌,且两者均为交界性可切除或局部晚期肿瘤的比例相似(78%比机器人组的 82%,p=0.82)。与开放 PD 组(中位数,6 [IQR 5 至 8] 天)相比,机器人 PD 组的 LOS 明显缩短(中位数,5 [IQR 4 至 7] 天,p<0.001)。机器人 PD 组中 4 天或更短的 LOS 观察到 40%,而开放 PD 组中只有 3%的患者(p<0.001)。总体再入院率无差异(机器人 PD 组为 10%,开放 PD 组为 12%,p=0.61)。多变量逻辑回归显示,与开放 PD 相比,机器人 PD 独立与 LOS 为 4 天或更短的可能性更高相关(优势比 22.4,p=0.001)。
在机器人 PD 程序中可以安全实施 ERAS 和早期出院途径。与开放 PD 相比,接受机器人 PD 的患者住院时间明显缩短,并发症或再入院率无增加,其中 40%的患者接受机器人 PD 的 LOS 为 4 天或更短。