From the Department of Pediatrics.
Department of Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Pediatr Infect Dis J. 2023 Apr 1;42(4):e124-e127. doi: 10.1097/INF.0000000000003816. Epub 2022 Dec 30.
We aimed to assess the risk factors, clinical features and microbial profiles of meningitis in neonates with suspected sepsis referred to a pediatric emergency. Over 13 months, 191 neonates were enrolled, of whom 64 (33.5%) had meningitis. There were no significant differences in risk factors or clinical features between infants with and without meningitis. Ninety-three neonates (49%) had culture-positive sepsis (109 isolates). Candida spp. (n = 29), coagulase-negative staphylococci (n = 28) and Klebsiella pneumoniae (n = 23) were the most common pathogens. Forty-one (53%) bacteria were multidrug resistant.
我们旨在评估疑似败血症的新生儿发生脑膜炎的风险因素、临床特征和微生物谱，并将其转诊至儿科急诊。在 13 个月的时间里，共纳入 191 例新生儿，其中 64 例（33.5%）患有脑膜炎。患有和不患有脑膜炎的婴儿在风险因素或临床特征方面没有显著差异。93 例新生儿（49%）患有培养阳性败血症（109 株分离物）。最常见的病原体是念珠菌属（n=29）、凝固酶阴性葡萄球菌（n=28）和肺炎克雷伯菌（n=23）。41 株（53%）细菌为多药耐药菌。
