From the Department of Medicine, New York Medical College, Valhalla, NY.
Department of Medicine, Tufts University School of Medicine, Boston, MA.
Cardiol Rev. 2024;32(5):402-407. doi: 10.1097/CRD.0000000000000520. Epub 2022 Dec 28.
The acute phase of severe acute respiratory syndrome coronavirus 2 [coronavirus disease (COVID)] infection has many well-documented cardiovascular manifestations, however, the long-term sequelae are less understood. In this focused review, we explore the risk factors, character, and rates of cardiovascular events in patients with Long COVID, which is defined as symptoms occurring more than 4 weeks following initial infection. Research has identified increased rates of cerebrovascular disease, dysrhythmias, ischemic and inflammatory heart disease, cardiopulmonary symptoms, and thrombotic events among those with Long COVID, though the risk rates and potential mechanisms behind each cardiovascular event vary. Finally, we discuss the current gaps in the literature as well as how COVID compares to other viral infections when it comes to causing long-term cardiovascular sequelae.
严重急性呼吸综合征冠状病毒 2（冠状病毒病（COVID））感染的急性期有许多记录在案的心血管表现，然而，其长期后果了解较少。在本次重点综述中，我们探讨了长新冠患者的心血管事件的危险因素、特征和发生率，长新冠定义为初次感染后 4 周以上出现症状。研究表明，长新冠患者的脑血管疾病、心律失常、缺血性和炎症性心脏病、心肺症状和血栓形成事件的发生率增加，尽管每种心血管事件的风险率和潜在机制有所不同。最后，我们讨论了文献中的当前空白，以及 COVID 在导致长期心血管后果方面与其他病毒感染相比的情况。
