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心脏手术后心房颤动的预防:文献复习及不同治疗方式比较。

Prevention of Atrial Fibrillation After Cardiac Surgery: A Review of Literature and Comparison of Different Treatment Modalities.

机构信息

From the Heart Center, Kuopio University Hospital, Kuopio, Finland.

Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.

出版信息

Cardiol Rev. 2024;32(3):248-256. doi: 10.1097/CRD.0000000000000499. Epub 2022 Dec 20.

Abstract

Atrial fibrillation is the most common arrhythmia to occur after cardiac surgery, with an incidence of 10% to 50%. It is associated with postoperative complications including increased risk of stroke, prolonged hospital stays and increased costs. Despite new insights into the mechanisms of atrial fibrillation, no specific etiologic factor has been identified as the sole perpetrator of the arrhythmia. Current evidence suggests that the pathophysiology of atrial fibrillation in general, as well as after cardiac surgery, is multifactorial. Studies have also shown that new-onset postoperative atrial fibrillation following cardiac surgery is associated with a higher risk of short-term and long-term mortality. Furthermore, it has been demonstrated that prophylactic medical therapy decreases the incidence of postoperative atrial fibrillation after cardiac surgery. Of note, the incidence of postoperative atrial fibrillation has not changed during the last decades despite the numerous preventive strategies and operative techniques proposed, although the perioperative and postoperative care of cardiac patients as such has improved.

摘要

心房颤动是心脏手术后最常见的心律失常,发生率为 10%至 50%。它与术后并发症有关,包括中风风险增加、住院时间延长和费用增加。尽管对心房颤动的机制有了新的认识,但尚未确定任何特定的病因因素是心律失常的唯一罪魁祸首。目前的证据表明,心房颤动的病理生理学,以及心脏手术后的病理生理学,是多因素的。研究还表明,心脏手术后新发的术后心房颤动与短期和长期死亡率增加相关。此外,已经证明预防性药物治疗可以降低心脏手术后术后心房颤动的发生率。值得注意的是,尽管提出了许多预防策略和手术技术,但在过去几十年中,术后心房颤动的发生率并没有改变,尽管心脏患者的围手术期和术后护理本身已经得到了改善。

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