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食管闭锁患者的主动脉固定术和后气管固定术治疗气管软化症的最新进展。

Update on aortopexy and posterior tracheopexy for tracheomalacia in patients with esophageal atresia.

机构信息

Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Department of Pediatric Surgery, Anjo Kosei Hospital, Anjo, Japan.

出版信息

Surg Today. 2024 Mar;54(3):211-219. doi: 10.1007/s00595-023-02652-6. Epub 2023 Feb 2.

Abstract

Despite improving the survival after repair of esophageal atresia (EA), the morbidity of EA repair remains high. Specifically, tracheomalacia (TM) is one of the most frequent complications of EA repair. Continuous positive airway pressure is generally applied for the treatment of TM. However, surgical intervention is required against an apparent life-threatening event or inability to perform extubation for a long period. According to our review, most cases of TM showed symptom improvement after aortopexy. The ratio of the trachea's lateral and anterior-posterior diameter at the brachiocephalic artery crossing the trachea, which reflects the compression of the trachea by the brachiocephalic artery, is a good indicator of aortopexy. Our finding suggests that most TM cases associated with EA may not be caused by tracheal fragility alone, but may involve blood vessel compression. Posterior tracheopexy (PT) is also an effective treatment for TM. Recently, open or thoracoscopic PT was able to be performed simultaneously with EA repair. In many cases, aortopexy or PT is a safe and effective surgical treatment for TM with EA. Other surgical procedures, such as external stenting, should be considered for patients with diffuse-type TM for whom aortopexy and PT appear relatively ineffective.

摘要

尽管食管闭锁(EA)修复后的存活率有所提高,但 EA 修复的发病率仍然很高。具体来说,气管软化(TM)是 EA 修复最常见的并发症之一。通常应用持续气道正压通气治疗 TM。然而,对于明显危及生命的事件或长时间无法进行拔管的情况,需要进行手术干预。根据我们的综述,大多数 TM 病例在主动脉固定术后症状均有改善。气管在头臂动脉穿过处的横向和前后直径之比反映了头臂动脉对气管的压迫,是主动脉固定术的一个很好的指标。我们的发现表明,大多数与 EA 相关的 TM 病例可能不是单纯由气管脆弱引起的,而是可能涉及血管压迫。后气管固定术(PT)也是 TM 的有效治疗方法。最近,EA 修复可同时进行开放性或胸腔镜下 PT。在许多情况下,主动脉固定术或 PT 是 EA 合并 TM 的一种安全有效的手术治疗方法。对于主动脉固定术和 PT 效果相对较差的弥漫性 TM 患者,应考虑其他手术治疗,如外部支架。

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