Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University (Shandong Eye Hospital), Jinan, China.
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Jinan, China ; and.
Cornea. 2023 Nov 1;42(11):1384-1390. doi: 10.1097/ICO.0000000000003191. Epub 2022 Dec 12.
The aim of this study was to compare corneal biomechanics treated with femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and small-incision lenticule extraction (SMILE) for myopia and astigmatism using the new corneal biomechanical parameters of Corvis ST II.
This was a prospective nonrandomized controlled study. Patients treated with FS-LASIK or SMILE between January 2018 and July 2018 were included. Corvis ST II was performed to measure corneal biomechanical parameters, including deformation amplitude ratio 2.0 mm (DA ratio 2.0 mm), integrated inverse radius (Integr Radius), stiffness parameter at first applanation (SP-A1), and Ambrosio relational thickness through the horizontal meridian (ARTh), preoperatively, 1 month postoperatively, and 6 months postoperatively. Pentacam pachymetry was used to assess the reduction in pachymetry.
Forty-five eyes underwent FS-LASIK, and 45 eyes underwent SMILE. The new parameters obtained by Corvis ST II between preoperative and postoperative measurements showed significant changes after FS-LASIK or SMILE (all P < 0.001). Postoperative SP-A1 significantly decreased in the 2 groups (108.88 ± 14.47-73.32 ± 13.2 in FS-LASIK and 105.79 ± 17.68-73.91 ± 14.81 in SMILE). Eyes with equal preoperative pachymetry, intraocular pressure, and spherical equivalents showed no significant differences in these new parameters measured using Corvis ST II ( all P > 0.05) between the 2 groups. The prediction of the laser platform overestimated the measured pachymetry reduction in the SMILE group (111.93 ± 15.18 μm vs. 87.16 ± 15.47 μm).
New corneal biomechanical parameters measured using Corvis ST II showed no significant differences between FS-LASIK and SMILE in eyes with homogeneous preoperative parameters. The laser software platform may have overestimated the actual corneal reduction in the eyes treated with SMILE.
本研究旨在使用新的角膜生物力学参数 Corvis ST II 比较飞秒激光辅助原位角膜磨镶术(FS-LASIK)和小切口微透镜提取(SMILE)治疗近视和散光的角膜生物力学。
这是一项前瞻性非随机对照研究。纳入 2018 年 1 月至 7 月期间接受 FS-LASIK 或 SMILE 治疗的患者。使用 Corvis ST II 测量角膜生物力学参数,包括变形幅度比 2.0mm(DA 比 2.0mm)、综合反转半径(Integr Radius)、第一次压平的刚性参数(SP-A1)和水平子午线的 Ambrosio 相关厚度(ARTh),分别于术前、术后 1 个月和术后 6 个月进行测量。Pentacam 角膜测厚仪用于评估角膜厚度的减少。
45 只眼接受 FS-LASIK,45 只眼接受 SMILE。Corvis ST II 测量的新参数在 FS-LASIK 或 SMILE 前后的测量结果显示明显变化(均 P<0.001)。两组术后 SP-A1 均明显下降(FS-LASIK 组为 108.88±14.47-73.32±13.2,SMILE 组为 105.79±17.68-73.91±14.81)。在术前角膜厚度、眼压和等效球镜相等的情况下,两组之间使用 Corvis ST II 测量的这些新参数无显著差异(均 P>0.05)。SMILE 组的激光平台对测量的角膜厚度减少量的预测值高于实际值(111.93±15.18μm 比 87.16±15.47μm)。
在术前参数均匀的患者中,使用 Corvis ST II 测量的新角膜生物力学参数在 FS-LASIK 和 SMILE 之间无显著差异。激光软件平台可能高估了 SMILE 治疗眼的实际角膜减少量。