Beijing Aier-Intech Eye Hospital, Beijing, China; and.
Aier School of Ophthalmology, Central South University, Changsha, China.
Cornea. 2023 Mar 1;42(3):383-388. doi: 10.1097/ICO.0000000000003213. Epub 2022 Dec 12.
This study aimed to present a novel technique for Descemet membrane endothelial keratoplasty (DMEK) in pseudophakic and vitrectomized eyes.
The sterile air was injected into the posterior eye segment (anterior vitreous cavity) as a barrier to prevent the fluid of the vitreous cavity flowing into the anterior chamber, levitating the iris-lens diaphragm to flatten the anterior chamber during the surgery. This approach assists in the unfolding of the donor endothelial graft, helping to perform DMEK surgery on patients with a posterior intraocular lens (IOL) and vitrectomy.
Four cases presented with corneal endothelial decompensation (pseudophakic bullous keratopathy) with previous IOL implantation and vitrectomy underwent DMEK with this technique. The Descemet endothelial graft unfolding time after air injection was 68.75 ± 8.96 seconds. No graft displacement occurred during the surgery. The uncorrected and corrected distance visual acuities were improved in 3 of 4 patients. The corneas were transparent, and there was no graft detachment observed postoperatively in all 4 patients.
The posterior eye segment air injection can reduce the difficulty of unfolding the DMEK graft in patients after IOL implantation and vitrectomy and the potential intraoperative and postoperative complications, allowing for easy performance of DMEK surgery on pseudophakic and vitrectomized eyes for corneal endothelial dysfunction.
本研究旨在介绍一种在人工晶状体眼和玻璃体切割眼行后弹力层内皮角膜移植术(DMEK)的新技术。
无菌空气被注入后节(前玻璃体腔)以形成屏障,防止玻璃体腔的液体流入前房,使虹膜-晶状体隔上浮以在手术中使前房变平。这种方法有助于供体内皮移植物的展开,有助于对有后房型人工晶状体和玻璃体切割的患者施行 DMEK 手术。
4 例有角膜内皮失代偿(人工晶状体眼大泡性角膜病变)的患者,既往行人工晶状体植入和玻璃体切割术,采用该技术行 DMEK。空气注入后,Descemet 内皮移植物展开时间为 68.75±8.96 秒。术中无移植物移位。4 例患者中的 3 例未矫正和矫正视力距离均有提高。所有 4 例患者的角膜均透明,术后无移植物脱离。
后节眼球内空气注射可以降低在人工晶状体眼和玻璃体切割术后患者中行 DMEK 移植物展开的难度和潜在的术中及术后并发症,使对角膜内皮功能障碍的人工晶状体眼和玻璃体切割眼行 DMEK 手术变得更容易。