Department of Cardiovascular Surgery, Okinawa Chubu Hospital, 281, Miyazato, Uruma-Shi, Okinawa, 904-2293, Japan.
J Cardiothorac Surg. 2023 Feb 2;18(1):57. doi: 10.1186/s13019-023-02155-y.
Open thoracic surgery (with infected lesion removal, prosthetic graft replacement, and pedicled tissue flap) has remained the main treatment for infected thoracic aortic aneurysms to date. Recent reports have highlighted good prognostic outcomes with thoracic endovascular aortic repair. However, thoracic endovascular aortic repair for infected thoracic aortic aneurysms is associated with an exacerbation of infection due to residual infected tissues. We discuss the control of refractory infections following endovascular treatment of infected thoracic aortic aneurysms.
An 81-year-old man, with a history of insulin-dependent diabetes mellitus and pancreaticoduodenectomy, presented to our emergency department with a fever. Blood tests revealed a markedly elevated leukocyte count, and contrast-enhanced computed tomography suggested a descending thoracic aortic pseudoaneurysm. We diagnosed the patient with an infected descending thoracic aortic aneurysm, and performed urgent thoracic endovascular aortic repair; he was started on an intravenous antibiotic treatment. Postoperatively, blood tests revealed a decreased leukocyte count and the patient remained afebrile. However, computed tomography revealed temporal enlargement of the abscess cavity; therefore, an abscess debridement and stent graft wrapping with pedicled latissimus dorsi muscle flaps were performed, which successfully controlled the infection. Six weeks after abscess debridement, the patient was switched to an oral antibiotic therapy. There was no evidence of recurrence of infection 8 months after the surgery.
A combined abscess debridement and pedicled tissue flap approach is useful for patients with poor surgical tolerance in whom infection control is difficult after thoracic endovascular aortic repair for infected thoracic aortic aneurysms. Pedicled latissimus dorsi muscle flaps are useful when using the omentum for pedicled tissue flap is difficult.
开放性胸部手术(包括感染病灶清除、人工移植物置换和带蒂组织瓣)一直是治疗感染性胸主动脉瘤的主要方法。最近的报告强调了胸主动脉腔内修复术的良好预后。然而,感染性胸主动脉瘤的胸主动脉腔内修复术与由于残留感染组织而导致感染恶化有关。我们讨论了控制感染性胸主动脉瘤血管内治疗后难治性感染的方法。
一名 81 岁男性,有胰岛素依赖型糖尿病和胰十二指肠切除术病史,因发热就诊于我院急诊科。血液检查显示白细胞计数显著升高,增强 CT 提示降胸主动脉假性动脉瘤。我们诊断该患者为感染性降胸主动脉瘤,并进行了紧急胸主动脉腔内修复术;开始给予静脉抗生素治疗。术后,血液检查显示白细胞计数降低,患者无发热。然而,CT 显示脓肿腔有暂时扩大;因此,进行了脓肿清创术和带蒂背阔肌瓣包裹支架移植物,成功控制了感染。脓肿清创术后 6 周,患者转为口服抗生素治疗。手术后 8 个月,无感染复发迹象。
对于手术耐受力差的患者,在感染性胸主动脉瘤的胸主动脉腔内修复术后感染控制困难时,联合脓肿清创术和带蒂组织瓣技术是有用的。当使用带蒂组织瓣困难时,带蒂背阔肌瓣是有用的。