Matsumura Rintaro, Koga Chikato, Tsujie Masanori, Mori Soichiro, Nishida Kentaro, Yasuyama Akinobu, Nomura Masatoshi, Yoshikawa Yukihiro, Sueda Toshinori, Miyagaki Hiromichi, Tei Mitsuyoshi, Goto Takayoshi, Akamaru Yusuke
Center for Medical Education and Training, Osaka Rosai Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):2016-2018.
A 73-year-old man underwent distal pancreatectomy for invasive pancreatic ductal carcinoma in 2018. He showed stenosis of sigmoid colon due to recurrence of pancreatic cancer and received transverse colostomy in 2020. One year after initiation of gemcitabine monotherapy, he complained of abdominal pain. CT images and colonoscopy revealed accumulation of mucus in sigmoid colon due to stenotic lesions. Because conservative treatment using antibiotics was not effective, we performed sigmoidectomy. Histological examination revealed that tubular adenocarcinoma located mainly in the muscularis propria invaded into the colonic mucosa. Immunohistochemical analysis showed positive staining for CK7, and negative for CK20. We diagnosed sigmoid colon metastases of pancreatic cancer.
一名73岁男性于2018年因侵袭性胰腺导管癌接受了胰体尾切除术。他因胰腺癌复发出现乙状结肠狭窄,并于2020年接受了横结肠造口术。吉西他滨单药治疗开始一年后,他主诉腹痛。CT图像和结肠镜检查显示,由于狭窄病变,乙状结肠内有黏液积聚。由于使用抗生素的保守治疗无效,我们进行了乙状结肠切除术。组织学检查显示,主要位于固有肌层的管状腺癌侵犯了结肠黏膜。免疫组化分析显示CK7染色阳性,CK20染色阴性。我们诊断为胰腺癌乙状结肠转移。