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[一例胆囊小细胞神经内分泌癌]

[A Case of Small Cell Neuroendocrine Carcinoma of the Gallbladder].

作者信息

Arai Shoichiro, Muroya Daisuke, Miyazaki Daiki, Hashimoto Kazuaki, Fukutomi Shogo, Akashi Masanori, Goto Yuichi, Sato Toshihiro, Sakai Hisamune, Akagi Yoshito, Hisaka Toru

机构信息

Dept. of Surgery, Kurume University.

出版信息

Gan To Kagaku Ryoho. 2022 Dec;49(13):1417-1419.

Abstract

A 76-year-old female was referred to our hospital with a tumor of the gallbladder using ultrasonography. CT and MRI of the abdomen and endoscopic ultrasonography revealed thickened walls of the body of her gallbladder. Endoscopic retrograde cholangiopancreatography was performed, adenocarcinoma was suspected based on bile cytology, and extended cholecystectomy with lymphadenectomy was performed. The postoperative pathological diagnosis was small cell neuroendcrine carcinoma. Three months after the surgery, CT revealed that she had multiple recurrences in the distant lymph node, and she died two months later. Gallbladder neuroendocrine carcinoma is rare and which is thought to have a poor prognosis, so effective multidisciplinary treatment must be required for this disease. In this case, it might need not to hesitate to perform preoperative endoscopic ultrasound guided fine needle aspiration(EUS-FNA).

摘要

一名76岁女性因胆囊肿瘤经超声检查后转诊至我院。腹部CT和MRI以及内镜超声检查显示其胆囊体部壁增厚。进行了内镜逆行胰胆管造影,根据胆汁细胞学怀疑为腺癌,并实施了扩大胆囊切除术及淋巴结清扫术。术后病理诊断为小细胞神经内分泌癌。术后三个月,CT显示她在远处淋巴结有多处复发,两个月后死亡。胆囊神经内分泌癌罕见,且预后较差,因此该病必须采取有效的多学科治疗。在这种情况下,可能需要毫不犹豫地进行术前内镜超声引导下细针穿刺抽吸术(EUS-FNA)。

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