Tsuneda Atsushi, Nojima Kouki, Fujimori Daisuke, Shoji Yasuhiro, Kadoya Naotaka
Dept. of Surgery, Toyama Rosai Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1528-1530.
Local control of disintegrating advanced breast cancer is often difficult because of the exudate, bleeding, and the foul odor. The current author encountered a case of large breast cancer with ulceration in which drug therapy and local control with Mohs' paste allowed disease control. The patient was a 61-year-old woman. There was a large ulcerated lump in her right breast, and exudate, bleeding, and a foul odor were present. The woman was diagnosed with hormone-sensitive mucinous carcinoma based on a biopsy, and diagnostic imaging revealed axillary lymph node metastasis and multiple metastases in both lungs. Mohs' paste was used locally, and local control was achieved after 1 month. A year and a half after the start of systemic drug therapy, the breast lump disappeared, and lung metastases and lymph node metastasis had almost disappeared. A CR has been maintained 3 years and 5 months later. Mohs' paste was extremely useful in achieving local control of exudation and bleeding from exposed unresected cancer. This was an excellent treatment in the patient's terminal stages and as part of local treatment in combination with systemic drug therapy.
由于存在渗液、出血及恶臭，对晚期破溃乳腺癌进行局部控制往往很困难。本文作者遇到一例伴有溃疡的巨大乳腺癌病例，通过药物治疗及使用莫氏糊剂进行局部控制实现了疾病控制。患者为一名61岁女性。其右乳有一个巨大的溃疡肿块，伴有渗液、出血及恶臭。经活检，该女性被诊断为激素敏感性黏液癌，诊断性影像学检查显示腋窝淋巴结转移及双肺多发转移。局部使用莫氏糊剂，1个月后实现了局部控制。全身药物治疗开始一年半后，乳房肿块消失，肺转移和淋巴结转移几乎消失。3年零5个月后维持了完全缓解状态。莫氏糊剂在实现对未切除的外露癌的渗液和出血的局部控制方面极其有用。这对于患者的终末期是一种很好的治疗方法，并且作为与全身药物治疗相结合的局部治疗的一部分。
