Fujisaki Shigeru, Takashina Motoi, Tomita Ryouichi, Sakurai Kenichi, Takayama Tadatoshi, Okamura Yukiyasu
Dept. of Surgery, Fujisaki Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1562-1564.
Primary duodenal cancer is a rare disease. We examined 8 resected cases of duodenal cancer at our hospital from June 2003 to February 2022. Patients with resected duodenal cancer had an average age of 69.3 years(45-84 years), with a male-female ratio of 3 : 5. Of the 8 cases, 6 cases were adenocarcinomas and 2 were neuroendocrine carcinomas. Among those with adenocarcinomas, 3 cases were Stage Ⅰ, while Stage ⅡA, ⅢA, and ⅢB accounted for one case each(UICC 8th edition). Five patients underwent a pancreaticoduodenectomy(PD), while 1 underwent partial duodenal resection. Except for 1 case of Stage ⅢB(death from tumor recurrence in 1 year), tumor recurrence was not observed in the 5 remaining cases(survival period; >1 month to >97 months). The patient with a pT3pN1M0, Stage Ⅲ neuroendocrine carcinoma underwent a partial duodenal resection due to poor cardiac and renal function. Meanwhile, the patient with a pT4pN0M0, Stage Ⅲ neuroendocrine carcinoma underwent a PD. The survival time was 123 months for the former(death from other diseases, no tumor recurrence)and 7 months for the latter(death from recurrence).
原发性十二指肠癌是一种罕见疾病。我们对2003年6月至2022年2月期间我院8例十二指肠癌切除病例进行了研究。十二指肠癌切除患者的平均年龄为69.3岁（45 - 84岁），男女比例为3:5。8例病例中，6例为腺癌，2例为神经内分泌癌。在腺癌患者中，3例为Ⅰ期，ⅡA期、ⅢA期和ⅢB期各占1例（国际抗癌联盟第8版）。5例患者接受了胰十二指肠切除术（PD），1例接受了十二指肠部分切除术。除1例ⅢB期患者（1年内因肿瘤复发死亡）外，其余5例均未观察到肿瘤复发（生存期；>1个月至>97个月）。1例pT3pN1M0Ⅲ期神经内分泌癌患者因心脏和肾功能差接受了十二指肠部分切除术。同时，1例pT4pN0M0Ⅲ期神经内分泌癌患者接受了胰十二指肠切除术。前者的生存时间为123个月（因其他疾病死亡，无肿瘤复发），后者为7个月（因复发死亡）。
