Hoshino Hiromitsu, Arai Isao, Endo Wakio, Matsumoto Takaaki, Kan Kazuomi
Dept. of Surgery, Hannan Chuo Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1622-1624.
A 73-year-old man underwent distal gastrectomy, D2 lymphadenectomy, and Billroth Ⅰ reconstruction for Type 3 advanced cancer in the lower corpus lesser curvature in 20XX. After postoperative adjuvant chemotherapy, he self-detected a mass in the left breast. It was diagnosed as breast cancer. He underwent mastectomy and axillary lymphadenectomy 16 months after gastric cancer surgery. After postoperative adjuvant chemotherapy, gastric or breast cancer did not recur. However, periodic upper gastrointestinal endoscopy revealed an 8-mm 0-Ⅱa lesion in the anterior wall of the remnant middle stomach(Group 5)80 months after gastric cancer surgery. Endoscopic submucosal dissection(ESD)was performed, and radical resection was achieved. Periodic upper gastrointestinal endoscopy was performed thereafter; an ectopic 0-Ⅱa lesion was detected in the greater curvature of the remnant middle stomach(Group 5)21 months after ESD. Since this lesion suggested massive submucosal invasion, total resection of the remnant stomach and Roux-en-Y reconstruction were performed. The postoperative course has been favorable, and the patient has been alive without recurrence for 6 months postoperatively. A long period passes before intestinal juice reflux induces progression of a chronic inflammatory gastric mucosal lesion to cancer in the remnant stomach. Thus, long-term endoscopic follow-up may be necessary.
一名73岁男性于20XX年因胃体小弯下部3型进展期癌接受了远端胃切除术、D2淋巴结清扫术及毕Ⅰ式重建术。术后辅助化疗后,他自行发现左侧乳房有肿物,被诊断为乳腺癌。在胃癌手术后16个月,他接受了乳房切除术及腋窝淋巴结清扫术。术后辅助化疗后,胃癌或乳腺癌均未复发。然而,胃癌手术后80个月,定期上消化道内镜检查发现残胃中部前壁(第5组)有一个8mm的0-Ⅱa病变。进行了内镜下黏膜下剥离术(ESD),实现了根治性切除。此后定期进行上消化道内镜检查;ESD术后21个月,在残胃中部大弯侧(第5组)发现一个异位0-Ⅱa病变。由于该病变提示有大量黏膜下浸润,遂进行了残胃全切除术及Roux-en-Y重建术。术后病程顺利,患者术后6个月无复发存活。肠液反流导致残胃慢性炎症性胃黏膜病变进展为癌症需要很长时间。因此,可能需要长期的内镜随访。