Engelmann B
Klinik für Gynäkologie und Geburtshilfe des Bereichs Medizin Karl-Marx-Universität Leipzig.
Zentralbl Gynakol. 1987;109(15):936-44.
In a retrospective study fetal risk was investigated in 138 pregnant women with hypertensive gestosis was investigated by means of selected parameters. We used the patho-physiologic classification and divided the patients in the groups of preeclampsia and chronic hypertension. By this it is possible to show in preeclampsia a larger shore of premature infants and a latent deficient fetal development. There is no significant difference of the average duration of pregnancy between the two groups. The gestosis symptoms of hypertension and proteinuria show differences with regard to their pathogenetic value. Correlative analyses between blood pressure values and proteinuria show predominantly inverse relations to pregnancy duration, birth weight of the newborn and pH-values in the umbilical artery post partum. On the other hand, they cannot be demonstrated in chronic hypertension. The results are being discussed in connection with possibly occurring differences of cardiocirculatory parameters and uteroplacental perfusion in either group of gestosis.
在一项回顾性研究中,通过选定的参数对138例患有妊娠高血压综合征的孕妇的胎儿风险进行了调查。我们采用病理生理分类法,将患者分为先兆子痫组和慢性高血压组。由此可以发现,先兆子痫组早产儿的比例更高,且存在潜在的胎儿发育不足。两组之间的平均孕期无显著差异。高血压和蛋白尿的妊娠高血压综合征症状在发病机制方面存在差异。血压值与蛋白尿之间的相关性分析显示,它们主要与孕期、新生儿出生体重以及产后脐动脉pH值呈负相关。另一方面,在慢性高血压中未发现这种相关性。结合妊娠高血压综合征两组中可能出现的心脏循环参数和子宫胎盘灌注差异对结果进行了讨论。