Gomez Casanovas Jose, Bartl Mery, Rincon-Rueda Laura, Loftis Christine E, Dulgheru Emilia
Internal Medicine, University of Texas Rio Grande Valley School of Medicine, Edinburg, USA.
Rheumatology Institute, Doctors Hospital at Renaissance, McAllen, USA.
Cureus. 2023 Jan 31;15(1):e34447. doi: 10.7759/cureus.34447. eCollection 2023 Jan.
Systemic lupus erythematosus (SLE) is a heterogenous, systemic disease characterized by the production of pathogenic autoantibodies against nuclear antigens. Although the most common cardiac manifestation of SLE is pericardial effusions, their progression to cardiac tamponade is rare and has an incidence between 1-3%. We describe a case of a 42-year-old Hispanic woman who presented with severe shortness of breath, vague chest pain, and hemodynamic compromise secondary to cardiac tamponade. The patient's underlying etiology of cardiac tamponade was attributed to a new diagnosis of SLE based on the 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology classification (EULAR/ACR) criteria for SLE. The patient's treatment consisted of a pericardial window and immunosuppressive therapy with corticosteroids, Mycophenolate, and hydroxychloroquine. This case aims to increase awareness of SLE as a possible differential diagnosis of cardiac tamponade in the appropriate clinical setting.
系统性红斑狼疮（SLE）是一种异质性的全身性疾病，其特征是产生针对核抗原的致病性自身抗体。虽然SLE最常见的心脏表现是心包积液，但进展为心脏压塞的情况很少见，发生率在1%至3%之间。我们描述了一例42岁的西班牙裔女性病例，该患者因心脏压塞出现严重呼吸急促、模糊的胸痛和血流动力学障碍。根据2019年欧洲抗风湿病联盟/美国风湿病学会（EULAR/ACR）SLE分类标准，该患者心脏压塞的潜在病因归因于新诊断的SLE。患者的治疗包括心包开窗术以及使用皮质类固醇、霉酚酸酯和羟氯喹进行免疫抑制治疗。本病例旨在提高对SLE作为心脏压塞在适当临床环境中可能鉴别诊断的认识。
