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[来自白令海不同区域的大王乌贼(Berryteuthis magister)胆碱酯酶与可逆性抑制剂的相互作用]

[Interaction of reversible inhibitors with the cholinesterase of the squid Berryteuthis magister from different areas of the Bering Sea].

作者信息

Kovalev N N, Rozengart E V

出版信息

Zh Evol Biokhim Fiziol. 1987 Jul-Aug;23(4):548-50.

PMID:3673373
Abstract

Studies have been made of the interaction of 13 onium reversible inhibitors with cholinesterase from the visual ganglia of the squid B. magister from various habitats (Kurile Islands, Olyutorsk-Navarin and Navarin-Alaskan regions). In some of the cases, differences were found between the enzymes from various specimens with respect to values of the generalized inhibitor constant (which is a measure of inhibitor effectiveness) and the pattern of inhibition. These data reveal intraspecific polymorphism in B. magister from the Bering Sea.

摘要

对13种鎓可逆抑制剂与来自不同栖息地(千岛群岛、奥柳托尔斯克-纳瓦林和纳瓦林-阿拉斯加地区)的大鳍乌贼视觉神经节中的胆碱酯酶之间的相互作用进行了研究。在某些情况下,发现不同标本的酶在广义抑制剂常数(衡量抑制剂有效性的指标)值和抑制模式方面存在差异。这些数据揭示了白令海大鳍乌贼的种内多态性。

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引用本文的文献

1
Interaction of cholinesterase from the visual ganglia of the Commander squid Berryteuthis magister from different areas of the range with reversible inhibitors.来自不同分布区域的大鳍乌贼(Berryteuthis magister)视觉神经节中的胆碱酯酶与可逆性抑制剂的相互作用。
Dokl Biochem Biophys. 2009 Sep-Oct;428:277-83. doi: 10.1134/s1607672909050147.
2
A comparative study of interaction of reversible onium inhibitors with cholinesterases of the Pacific squid Todarodes pacificus and some other vertebrates.
Dokl Biochem Biophys. 2009 May-Jun;426:152-7. doi: 10.1134/s1607672909030077.
3
Conformational characteristics of the structure of acetylcholine amide derivatives and the specificity of their action as reversible inhibitors of cholinesterases of different animals.乙酰胆碱酰胺衍生物的结构构象特征及其作为不同动物胆碱酯酶可逆抑制剂的作用特异性。
Dokl Biochem Biophys. 2005 Nov-Dec;405:450-3. doi: 10.1007/s10628-005-0137-0.
4
Different sensitivities of cholinesterases of the comandor squids (Berryteuthis magister) from different parts of its range to bislupinine derivatives of dicarboxylic acids.来自其分布范围不同区域的指挥官鱿鱼(Berryteuthis magister)不同部位的胆碱酯酶对二羧酸双卢平宁衍生物的不同敏感性。
Dokl Biochem Biophys. 2003 Jan-Feb;388:46-8. doi: 10.1023/a:1022564730930.