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[来自白令海不同区域的大王乌贼(Berryteuthis magister)胆碱酯酶与可逆性抑制剂的相互作用]

[Interaction of reversible inhibitors with the cholinesterase of the squid Berryteuthis magister from different areas of the Bering Sea].

作者信息

Kovalev N N, Rozengart E V

出版信息

Zh Evol Biokhim Fiziol. 1987 Jul-Aug;23(4):548-50.

PMID:3673373
Abstract

Studies have been made of the interaction of 13 onium reversible inhibitors with cholinesterase from the visual ganglia of the squid B. magister from various habitats (Kurile Islands, Olyutorsk-Navarin and Navarin-Alaskan regions). In some of the cases, differences were found between the enzymes from various specimens with respect to values of the generalized inhibitor constant (which is a measure of inhibitor effectiveness) and the pattern of inhibition. These data reveal intraspecific polymorphism in B. magister from the Bering Sea.

摘要

对13种鎓可逆抑制剂与来自不同栖息地(千岛群岛、奥柳托尔斯克-纳瓦林和纳瓦林-阿拉斯加地区)的大鳍乌贼视觉神经节中的胆碱酯酶之间的相互作用进行了研究。在某些情况下,发现不同标本的酶在广义抑制剂常数(衡量抑制剂有效性的指标)值和抑制模式方面存在差异。这些数据揭示了白令海大鳍乌贼的种内多态性。

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