Breadon G E, Kern E B, Neel H B
Arch Otolaryngol. 1979 Feb;105(2):75-80. doi: 10.1001/archotol.1979.00790140021004.
This study evaluated autografts of bone and cartilage, uncrushed and crushed, in the perichondrial space of the ear and subcutaneously in the paraspinal region in rabbits six weeks and six months after transplantation. The results support the belief that in a clinical setting it is important to preserve perichondrium because it facilitates growth of new cartilage. This study suggests that when autogenous tissue is to be used for subcutaneous augmentation, it is best to use crushed or uncrushed cartilage or uncrushed bone because they remain viable. In the perichondrial space, crushed and uncrushed cartilage grafts not only remain viable but also induce growth of new cartilage and bone. Autogenous crushed bone does not survive in the perichondrial space of the rabbit ear.
本研究评估了未粉碎和粉碎的骨与软骨自体移植物,在兔耳软骨膜间隙以及脊柱旁区域皮下移植6周和6个月后的情况。结果支持以下观点:在临床环境中,保留软骨膜很重要,因为它有助于新软骨的生长。本研究表明,当使用自体组织进行皮下填充时,最好使用粉碎或未粉碎的软骨或未粉碎的骨,因为它们能保持活力。在软骨膜间隙,粉碎和未粉碎的软骨移植物不仅能保持活力,还能诱导新软骨和骨的生长。自体粉碎骨在兔耳软骨膜间隙无法存活。