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圣保罗医院就诊的急性冠状动脉综合征患者的治疗结果

Treatment Outcomes of the Acute Coronary Syndrome Among Patients Attending St. Paul Hospital.

作者信息

Anagaw Yeniewa Kerie, Yeheyis Marshet Mulugeta, Ayenew Wondim, Bizuneh Gizachew Kassahun

机构信息

Department of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Internal Medicine St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Ther Clin Risk Manag. 2023 Jan 27;19:105-114. doi: 10.2147/TCRM.S382422. eCollection 2023.

Abstract

BACKGROUND

Acute coronary syndrome (ACS) patients need intense therapy and diagnostic evaluation for improved treatment. In Ethiopia, where patient deaths and hospital stays are rising, the ACS treatment is thought to be not very effective.

METHODS

A retrospective cross-sectional study was conducted at St. Paul Hospital. The data were collected from patients medical records using a structured data abstraction checklist from 2018 to 2020. The data was entered, analyzed, and interpreted using SPSS version 24 software.

RESULTS

Of 157 ACS patients, 69 (43.9%) had a STEMI diagnosis. Age was 63.69 years on average (SD: 8.23). The typical amount of time between the onsets of ACS symptoms to hospital presentation was 79.3 hours (3.3 days). For 104 (66.2%) patients, hypertension was the main risk factor for the development of ACS. Killip class III and IV patients made up about 3.8% of the ACS patients at St. Paul hospital. An EF of less than 40% was present in 36.3% of patients. Loading doses of aspirin (90.4%), anticoagulants (14%), beta-blockers (82.8%), statins (86%), clopidogrel (7.6%), and nitrates (2.5%) are among the medications taken inside hospitals. Of 157 ACS patients, 6 (3.8%) patients with medical records examined died while receiving treatment in the hospital, while 151 (96.2%) patients were discharged alive.

CONCLUSION

STEMI was the most common diagnosis for ACS patients at St. Paul Hospital. The two main hospital events for these patients were CHF and cardiogenic shock.

摘要

背景

急性冠状动脉综合征(ACS)患者需要强化治疗和诊断评估以改善治疗效果。在埃塞俄比亚,患者死亡率和住院时间不断上升,ACS治疗被认为效果不佳。

方法

在圣保罗医院进行了一项回顾性横断面研究。使用结构化数据提取清单从2018年至2020年收集患者病历数据。使用SPSS 24版软件录入、分析和解释数据。

结果

157例ACS患者中,69例(43.9%)诊断为ST段抬高型心肌梗死(STEMI)。平均年龄为63.69岁(标准差:8.23)。ACS症状发作至入院的平均时间为79.3小时(3.3天)。104例(66.2%)患者中,高血压是发生ACS的主要危险因素。圣保罗医院Killip III级和IV级患者约占ACS患者的3.8%。36.3%的患者左心室射血分数(EF)低于40%。住院期间使用的药物包括负荷剂量的阿司匹林(90.4%)、抗凝剂(14%)、β受体阻滞剂(82.8%)、他汀类药物(86%)、氯吡格雷(7.6%)和硝酸盐类药物(2.5%)。157例ACS患者中,有病历记录的6例(3.8%)患者在住院治疗期间死亡,151例(96.2%)患者存活出院。

结论

STEMI是圣保罗医院ACS患者最常见的诊断。这些患者主要的两种住院事件是心力衰竭和心源性休克。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8a/9888011/95c8579bd349/TCRM-19-105-g0001.jpg

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