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[动脉粥样硬化时人类软脑膜动脉内膜的结构改变]

[Structural transformations of the intima of arteries of the human pia mater in atherosclerosis].

作者信息

Chertok V M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(7):992-5.

PMID:3673399
Abstract

Using scanning and transmission microscopy, the structural transformations of the internal coating of the pial arteries have been investigated in patients with atherosclerosis (grade I+). The examination has revealed marked changes in the intima expressed in variable degree disorganization of the microrelief of the luminal surface of the vessels (diminution in the height and disappearance of the folds, their inadequate orientation, formation of spherical protrusions and crater-like cavities) and in transformations of the structural organization of the endothelium and subendothelial layer (intensification of pinocytosis, impairment of the integrity of intercellular contacts, lipidosis of endothelial cells, subendothelial edema).

摘要

利用扫描显微镜和透射显微镜,对动脉粥样硬化(I+级)患者软脑膜动脉内涂层的结构转变进行了研究。检查发现,内膜有明显变化,表现为血管腔表面微浮雕的不同程度紊乱(褶皱高度降低和消失、其方向不当、球形突起和火山口样腔的形成),以及内皮和内皮下层结构组织的转变(胞饮作用增强、细胞间接触完整性受损、内皮细胞脂质沉积、内皮下水肿)。

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