Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA.
Twin Res Hum Genet. 2022 Dec;25(6):211-225. doi: 10.1017/thg.2023.1. Epub 2023 Feb 3.
The University of Minnesota has played an important role in the resurgence and eventual mainstreaming of human behavioral genetics in psychology and psychiatry. We describe this history in the context of three major movements in behavioral genetics: (1) radical eugenics in the early 20th century, (2) resurgence of human behavioral genetics in the 1960s, largely using twin and adoption designs to obtain more precise estimates of genetic and environmental influences on individual differences in behavior; and (3) use of measured genotypes to understand behavior. University of Minnesota scientists made significant contributions especially in (2) and (3) in the domains of cognitive ability, drug abuse and mental health, and endophenotypes. These contributions are illustrated through a historical perspective of major figures and events in behavioral genetics.
明尼苏达大学在心理学和精神病学中人类行为遗传学的复兴和最终主流化方面发挥了重要作用。我们在行为遗传学的三个主要运动的背景下描述了这段历史：（1）20 世纪初的激进优生学，（2）20 世纪 60 年代人类行为遗传学的复兴，主要使用双胞胎和收养设计来获得更精确的遗传和环境对行为个体差异的影响估计；以及（3）使用测量的基因型来理解行为。明尼苏达大学的科学家们在认知能力、药物滥用和精神健康以及内表型等领域做出了重大贡献，尤其是在（2）和（3）中。这些贡献通过行为遗传学的主要人物和事件的历史视角来说明。
