Instituto de Catálisis y Petroleoquímica, CSIC. C/Marie Curie 2, 28049Madrid, Spain.
J Phys Chem Lett. 2023 Feb 16;14(6):1452-1456. doi: 10.1021/acs.jpclett.2c03940. Epub 2023 Feb 3.
There is great interest in the use of Monolayer-Protected Gold Clusters (AuMPCs) as nanoscale capacitors in aqueous media for nanobiotechnological applications, such as bioelectrocatalysts, biofuel cells, and biosensors. However, AuMPCs exhibiting subattofarad double-layer capacitance at room temperature, and the resolution of single-electron charging, has been mainly obtained in an organic medium with nonfunctional capping ligands. We report here the synthesis of Thioctic Acid Monolayer-Protected Au Clusters (TA-AuMPCs) showing electrochemical single electron quantized capacitance charging in organic and aqueous solutions and when immobilized onto different self-assembled monolayer-modified gold electrodes. The presence of functional carboxylic groups opens a simple strategy for interfacing a nanoparticle assembly to biomolecules for their use as electron donors or acceptors in biological electron transfer reactions.
人们对在水相介质中使用单层保护金纳米团簇（AuMPCs）作为纳米级电容器非常感兴趣，因为其在纳米生物技术应用中有很多用途，如生物电催化剂、生物燃料电池和生物传感器。然而，在室温下具有亚阿特法拉德双层电容且能分辨单个电子充电的 AuMPCs 主要是在具有非功能化配体的有机介质中获得的。我们在此报告了一种巯基乙酸单层保护金纳米团簇（TA-AuMPCs）的合成方法，该方法在有机和水溶液中以及固定在不同自组装单分子层修饰的金电极上时，均表现出电化学单电子量子化电容充电。功能性羧酸基团的存在为纳米颗粒组装体与生物分子连接提供了一种简单策略，可将其用作生物电子转移反应中的电子供体或受体。
