Mislang Anna R A, Mangoni Arduino A, Molga Angela, Jena Swatee, Koczwara Bogda
Department of Medical Oncology, Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
Discipline of Clinical Pharmacology, College of Medicine and Public Health, Flinders University, Department of Clinical Pharmacology, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, SA, Australia.
Age Ageing. 2023 Feb 1;52(2). doi: 10.1093/ageing/afad008.
Older adults represent a growing population amongst cancer survivors who require specific consideration given the complex and largely unknown interactions between cancer-related concerns and age-related conditions. The increasing use of geriatric assessment (GA) has enabled oncologists to appropriately assess older patients' overall health status, personalise anti-cancer treatment and improve survival. However, whilst current research and practice focus on improving the management of older adults with cancer in the acute setting, the progress in the field of survivorship research in geriatric oncology is lagging. As cancer survivorship is a continuum, planning for a healthy survivorship should start at the time of cancer diagnosis. GA can play an important role in identifying potential survivorship issues and optimising delivery of survivorship care. A goal-directed, patient-focused geriatric survivorship care plan that involves a multidisciplinary team provides a framework for a personalised delivery of survivorship care in this patient group and there is a need for tailored interventions that support self-management and care integration. Research on the impact of cancer and its treatment on geriatric-specific outcomes needs to be prioritised through global initiatives to encompass a diverse and heterogenous population of adult cancer survivors.
老年癌症幸存者人数日益增加，鉴于癌症相关问题与年龄相关状况之间复杂且大多未知的相互作用，这一群体需要特别关注。老年评估（GA）的使用日益增多，使肿瘤学家能够适当地评估老年患者的整体健康状况，使抗癌治疗个性化并提高生存率。然而，尽管目前的研究和实践侧重于改善老年癌症患者在急性治疗阶段的管理，但老年肿瘤学的生存研究领域进展滞后。由于癌症生存是一个连续过程，健康生存计划应在癌症诊断时就开始。老年评估在识别潜在的生存问题和优化生存护理的提供方面可以发挥重要作用。一个以目标为导向、以患者为中心的老年生存护理计划，由多学科团队参与，为该患者群体个性化提供生存护理提供了一个框架，并且需要有支持自我管理和护理整合的定制干预措施。需要通过全球倡议优先开展关于癌症及其治疗对老年特定结局影响的研究，以涵盖成年癌症幸存者这一多样化和异质性群体。
