评价屈螺酮炔雌醇片（妈富隆）作为流产后非甾体避孕药的可接受性、安全性和续用率。
Evaluation of acceptability, safety, and continuation rates of centchroman as postabortion nonsteroidal contraceptive pill.
机构信息
Department of Obstetrics and Gynaecology, VMMC & Safdarjung Hospital, New Delhi, India.
Department of Obstetrics and Gynaecology, VMMC & Safdarjung Hospital, New Delhi, India.
出版信息
Contraception. 2023 May;121:109961. doi: 10.1016/j.contraception.2023.109961. Epub 2023 Feb 1.
OBJECTIVES
To evaluate acceptability, safety, and continuation rates of centchroman following abortion.
STUDY DESIGN
Prospective, observational study. Following spontaneous/induced abortion, women were offered centchroman, 30-mg tablet twice weekly for first 3 months, then once weekly with 1 year of follow-up.
RESULTS
Of 120 women who opted for centchroman, continuation rate was 91% at 12 months. There was one case of user failure and one method failure and 26% had infrequent cycles.
CONCLUSIONS
Centchroman is safe, effective, has good acceptance, and continuation rate post abortion with infrequent menstrual cycles as the main limiting factor for its continuation.
IMPLICATIONS
Centchroman, available in Government scheme for contraception, has good acceptance and continuation rate post abortion. Its inclusion in contraceptive choices offered for postabortion contraception can go a long way in spacing of pregnancies, decreasing repeated unintended pregnancies, unsafe abortions, maternal morbidity, and mortality.
目的
评估屈螺酮用于流产后的可接受性、安全性和续用率。
研究设计
前瞻性观察性研究。在自然/人工流产后，为女性提供屈螺酮，30 毫克片剂，前 3 个月每周 2 次，然后每周 1 次，随访 1 年。
结果
120 名选择屈螺酮的女性中，12 个月的续用率为 91%。有 1 例使用者失败和 1 例方法失败，26%的女性月经周期不规律。
结论
屈螺酮在流产后是安全、有效、具有良好的可接受性和续用率的，以月经周期不规律为主要限制因素。
意义
屈螺酮可在政府避孕计划中获得，在流产后具有良好的接受度和续用率。将其纳入流产后避孕选择中，可以在间隔妊娠、减少重复非意愿妊娠、不安全流产、孕产妇发病率和死亡率方面发挥重要作用。
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