Wang Xueli, Wise Jessica C, Stewart Allison J
School of Veterinary Science, The University of Queensland, Gatton Campus, Building 8114, Inner Ring Road, Gatton, Queensland 4343, Australia.
School of Veterinary Science, The University of Queensland, Gatton Campus, Building 8114, Inner Ring Road, Gatton, Queensland 4343, Australia.
Vet Clin North Am Equine Pract. 2023 Apr;39(1):89-98. doi: 10.1016/j.cveq.2022.11.009. Epub 2023 Feb 1.
Hendra virus (HeV) emerged as a zoonotic pathogen in the 1990s, causing low morbidity but high mortality in humans and horses. Pteropid bats are the natural reservoir of HeV and other important zoonotic viruses such as Nipah and Ebola viruses. Equivac HeV, manufactured by Zoetis (Parkville, Victoria, Australia), is the only commercially available vaccine for horses. There is no commercial vaccine for humans. The epidemiology, clinical features, pathology, diagnosis, management, and prevention of HeV will be reviewed.
亨德拉病毒(HeV)于20世纪90年代作为一种人畜共患病原体出现,在人类和马匹中发病率低但死亡率高。狐蝠是HeV以及其他重要人畜共患病病毒(如尼帕病毒和埃博拉病毒)的天然宿主。由硕腾公司(澳大利亚维多利亚州帕克维尔)生产的Equivac HeV是唯一可用于马匹的商业疫苗。目前尚无用于人类的商业疫苗。本文将对HeV的流行病学、临床特征、病理学、诊断、管理和预防进行综述。