Adelaide Dental School, The University of Adelaide, Adelaide, SA, Australia.
Adelaide Dental School, The University of Adelaide, Adelaide, SA, Australia.
Arch Oral Biol. 2023 Mar;147:105633. doi: 10.1016/j.archoralbio.2023.105633. Epub 2023 Jan 28.
Our aims were to assess the prevalence of hypodontia in unilateral hemifacial microsomia (HFM), and to compare tooth (crown) size between affected and unaffected sides.
In a retrospective cross-sectional study of South Australians, computed tomography (CT) scans were used to assess hypodontia and crown size (mesiodistal length, buccolingual width and crown height). The inclusion criteria were the absence of other congenital anomalies and the availability of CT scans. The exclusion criteria were the lack of extraction history or reproducible landmarks for morphometric assessment. The final sample comprised 41 participants in both dentitions, including 32 children and 9 adults (median age 13.9 years, range 0.4 - 47.6 years; 19 males and 22 females). Hypodontia was assessed in all participants, and the permanent crown size in 30 (73.2%) participants. Linear mixed-effects models were performed to determine if crown size was significantly different between the two sides, controlling for sex, HFM severity, and tooth and jaw type.
Hypodontia occurred in none of the participants in the primary dentition, but in 6/30 (20%) participants in the permanent dentition (3/30 each on the affected and unaffected sides). There was no significant difference in the mean crown dimensions between the two sides, but the crown size was larger in males (p < 0.05), except for mesiodistal length, and became progressively smaller with increased HFM severity (p < 0.05).
Hypodontia spared the primary dentition but featured prominently in the permanent dentition. The permanent crown dimensions were unaltered between the two sides.
评估单侧颜面裂畸形（HFM）患者中缺牙的发生率，并比较患侧和健侧牙齿（牙冠）大小。
在南澳大利亚州的一项回顾性病例交叉研究中，使用计算机断层扫描（CT）评估缺牙和牙冠大小（近远中长度、颊舌宽度和牙冠高度）。纳入标准为无其他先天性异常和 CT 扫描可用。排除标准为缺乏拔牙史或形态计量评估的可重复性标志。最终样本包括 41 名双侧牙齿的参与者，包括 32 名儿童和 9 名成人（中位年龄 13.9 岁，范围 0.4-47.6 岁；男性 19 名，女性 22 名）。所有参与者均评估了缺牙情况，30 名参与者（73.2%）评估了恒牙牙冠大小。采用线性混合效应模型，控制性别、HFM 严重程度、牙和颌骨类型，确定牙冠大小是否在两侧有显著差异。
在乳牙列中，没有参与者发生缺牙，但在恒牙列中有 6/30 名（各有 3 名）参与者发生缺牙（患侧和健侧各有 3 名）。两侧牙冠平均尺寸无显著差异，但男性牙冠尺寸较大（p<0.05），除近远中长度外，随着 HFM 严重程度的增加，牙冠尺寸逐渐减小（p<0.05）。
缺牙未累及乳牙列，但在恒牙列中表现突出。两侧恒牙牙冠尺寸无变化。
