Kahramanmaraş Sutçu Imam University, Faculty of Health Science, Department of Physiotherapy and Rehabilitation, Kahramanmaras, Turkey.
Kahramanmaraş Sutçu Imam University, Faculty of Health Science, Department of Physiotherapy and Rehabilitation, Kahramanmaras, Turkey.
Mult Scler Relat Disord. 2023 Mar;71:104541. doi: 10.1016/j.msard.2023.104541. Epub 2023 Jan 29.
The aim is to compare the effects of different electrical stimulations on pain, functional capacity and quality of life in patients with Multiple Sclerosis (pwMS).
40 pwMS were included in the study, randomized by simple random method and divided into 2 groups. Low-frequency Transkutaneal Electric Stimulation (TENS) was applied to 1st group and Interferential current was applied to 2nd group for 30 min 5 days/a week for 4 weeks. For pain severity Visual Analogue Scale (VAS), for neuropathic pain the LANSS questionnaire was used. Functional capacity was evaluated with the 2-minute walk test (2MWT) and quality of life was evaluated with the 'Multiple Sclerosis International Quality of Life Scale (MusiQol)'.
The most severe and mean VAS and LANSS results significiantly decreased, 2MWT results significiantly increased in two groups (p<0.05). A significiant increase was found in all sub-headings of the MusiQol, except for the relationship with the health system in TENS group (p<0.05). An increase was found in the total score, activities of daily living, well-being, relationship with friends, relationship with family, sexual life, rejection sub-headings of the MusiQol in IFC group (p<0.05). There was no significant difference between the groups in terms of VAS, LANSS, 2MWT and MusiQol (p>0.05).
In this study, it was found that interference current and TENS applications decrease pain and increase functional capacity. However, it was determined that TENS application was a more effective method in increasing the quality of life.
NCT05110586.
比较不同电刺激对多发性硬化症（pwMS）患者疼痛、功能能力和生活质量的影响。
本研究纳入 40 名 pwMS，采用简单随机方法进行分组，分为两组。第一组应用低频经皮电刺激（TENS），第二组应用干扰电流，每周 5 天，每天 30 分钟，共 4 周。疼痛严重程度采用视觉模拟评分法（VAS）评估，神经病理性疼痛采用 LANSS 问卷评估。功能能力采用 2 分钟步行试验（2MWT）评估，生活质量采用多发性硬化症国际生活质量量表（MusiQol）评估。
两组的 VAS 和 LANSS 评分均显著降低，2MWT 评分显著升高（p<0.05）。MusiQol 除 TENS 组与卫生系统相关的子量表外，其他子量表的评分均显著升高（p<0.05）。IFC 组的 MusiQol 总分、日常生活活动、幸福感、与朋友的关系、与家人的关系、性生活、排斥等子量表评分均显著升高（p<0.05）。两组 VAS、LANSS、2MWT 和 MusiQol 评分均无显著差异（p>0.05）。
本研究发现，干扰电流和 TENS 应用均可减轻疼痛，提高功能能力。然而，TENS 应用在提高生活质量方面更为有效。
NCT05110586。
