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DMEK术后植片脱离后的自发性角膜恢复

Spontaneous corneal clearance after graft detachment in DMEK.

作者信息

Fernández-Vega-Cueto L, Lisa C, Vasanthananthan K, Madrid-Costa D, Alfonso J F, Melles G R J

机构信息

Instituto Oftalmológico Fernández-Vega, Oviedo, Asturias, Spain.

Instituto Oftalmológico Fernández-Vega, Oviedo, Asturias, Spain.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2023 Mar;98(3):170-174. doi: 10.1016/j.oftale.2022.11.006. Epub 2023 Feb 2.

DOI:10.1016/j.oftale.2022.11.006
PMID:36738920
Abstract

Descemet Membrane detachment is a potential complication after Descemet Membrane Endothelial Keratoplasty (DMEK). Here, we present a unique case of a DMEK surgery in a complicated eye that suffered a nearly complete DMEK graft detachment and later a graft opacification with a pseudo-anterior chamber. In Mid-November 2020, a planned DMEK was performed in a 64-year-old male patient due to corneal decompensation. Four months after DMEK, a fibrotic DMEK graft was seen across the anterior chamber with a pseudo-anterior chamber; however, the recipient cornea showed complete clearance with an endothelial cell count of about 1204 cells/mm2 and a best-corrected visual acuity of 20/25. Three months later, we observed a significant opacification of the detached graft, and the best-corrected distance visual acuity decreased to 20/63. We proceeded with the graft removal without performing a second DMEK. Ten months after graft removal, the cornea remained clear with an endothelial cell count of about 510 cells/mm, and the best-corrected visual acuity was 20/25.

摘要

后弹力层脱离是后弹力层内皮角膜移植术(DMEK)后的一种潜在并发症。在此,我们报告一例复杂眼行DMEK手术的独特病例,该眼发生了几乎完全的DMEK植片脱离,随后出现植片混浊并伴有假性前房。2020年11月中旬,因角膜失代偿,为一名64岁男性患者实施了计划性DMEK手术。DMEK术后4个月,可见纤维化DMEK植片横跨前房并伴有假性前房;然而,受体角膜完全清亮,内皮细胞计数约为1204个细胞/mm²,最佳矫正视力为20/25。3个月后,我们观察到脱离的植片出现明显混浊,最佳矫正远视力降至20/63。我们未进行第二次DMEK手术,而是直接取出了植片。植片取出10个月后,角膜保持清亮,内皮细胞计数约为510个细胞/mm,最佳矫正视力为20/25。

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