Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Autoimmun Rev. 2023 Apr;22(4):103286. doi: 10.1016/j.autrev.2023.103286. Epub 2023 Feb 2.
Both COVID-19 and autoimmune bullous diseases represent potentially life-threatening conditions. Autoimmunity has been a special focus during the COVID-19 pandemic considering the possible detrimental mutual influence between COVID-19 and autoimmune disorders as well as their supposed induction or triggering by SARS-CoV-2 vaccines. There is a growing need to assess the impact of the current pandemic particularly in patients with autoimmune bullous diseases requiring potent and long-term immunosuppressive treatments. This review provides the relevant state-of-the-art knowledge, including our own research, about immunobullous diseases in relation to COVID-19 and summarizes expert perspectives on their management throughout the pandemic.
COVID-19 和自身免疫性大疱性疾病均代表潜在的危及生命的病症。鉴于 COVID-19 与自身免疫性疾病之间可能存在相互不利影响,以及它们可能由 SARS-CoV-2 疫苗引发或触发,在 COVID-19 大流行期间,自身免疫一直是一个特别关注的问题。目前特别需要评估当前大流行对自身免疫性大疱性疾病患者的影响,这些患者需要进行强效和长期的免疫抑制治疗。这篇综述提供了与 COVID-19 相关的免疫性大疱性疾病的相关最新知识,包括我们自己的研究,并总结了专家在整个大流行期间对其治疗的观点。