超声腱鞘炎：血清阴性类风湿关节炎患者的鉴别特征。
Ultrasound tenosynovitis: A differential feature of patients with seronegative rheumatoid arthritis.
机构信息
Rheumatology Unit, Hospital Italiano de La Plata, La Plata, Argentina.
Rheumatology Unit, Hospital Italiano de La Plata, La Plata, Argentina.
出版信息
Reumatol Clin (Engl Ed). 2023 Feb;19(2):63-66. doi: 10.1016/j.reumae.2022.04.001.
OBJECTIVE
To identify differential features between patients with seropositive and seronegative rheumatoid arthritis (RA).
METHOD
Prospective cohort study, including patients who were admitted for polyarthralgia. At baseline was performed: laboratory studies, X-rays of hands and feet, ultrasound of both hands with power Doppler technique, clinical data and clinimetry. In subsequent visits the definitive diagnosis of RA was established or not. It was considered as seronegative RA when patients were negative for both RF and ACPAs.
RESULTS
746 patients were included, of which 128 (17.1%) ended with a final diagnosis of RA. Of these 128 patients, 87 (67.9%) were seropositive RA, while 41 (32%) were seronegative RA. The only feature that showed significant differences was the presence of tenosynovitis detected by ultrasound with a positive power Doppler signal, 13.7% of the patients with seropositive RA vs 41.6% of the patients with seronegative RA (p=0.0028).
CONCLUSION
The only differential feature of patients with seronegative RA was the higher proportion of tenosynovitis detected by ultrasound.
目的
确定血清阳性和血清阴性类风湿关节炎（RA）患者之间的差异特征。
方法
前瞻性队列研究，纳入因多关节痛就诊的患者。在基线时进行了实验室研究、双手和双脚的 X 光检查、双手的超声检查（包括能量多普勒技术）、临床数据和临床计量学检查。在随后的就诊中，确定了是否存在明确的 RA 诊断。当患者 RF 和 ACPA 均为阴性时，将其归类为血清阴性 RA。
结果
共纳入 746 例患者，其中 128 例（17.1%）最终诊断为 RA。在这 128 例患者中，87 例（67.9%）为血清阳性 RA，41 例（32%）为血清阴性 RA。唯一显示出显著差异的特征是超声检查中阳性能量多普勒信号提示的腱鞘炎存在，血清阳性 RA 患者中为 13.7%，血清阴性 RA 患者中为 41.6%（p=0.0028）。
结论
血清阴性 RA 患者的唯一差异特征是超声检查中腱鞘炎的比例更高。
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