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理解我们所做之事的意义——如何将证据应用于临床实践。

Making SENSE of what we do - How to bring evidence to clinical practice.

作者信息

Kellinghaus Christoph

机构信息

Department of Neurology, Klinikum Osnabrück, Am Finkenhügel 1, 49076 Osnabrück, Germany.

出版信息

Epilepsy Behav. 2023 Mar;140:109103. doi: 10.1016/j.yebeh.2023.109103. Epub 2023 Feb 3.

DOI:10.1016/j.yebeh.2023.109103
PMID:36739635
Abstract

Status epilepticus is a frequent neurological emergency. Several audits and registries have enhanced our knowledge regarding patient demography, etiology, treatment, and outcome. Several large registries have also contributed significantly to current treatment guidelines that emphasize the importance of instant and effective treatment onset. Large registries also document that deviation from these treatment guidelines is not the exception but the rule. Therefore, careful analysis of the treatment pathways as well as balanced intervention efforts are necessary to overcome the gap between knowledge and action. This paper was presented at the 8th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures held in September 2022.

摘要

癫痫持续状态是一种常见的神经科急症。多项审计和登记系统增进了我们对患者人口统计学、病因、治疗及预后的了解。多个大型登记系统也为当前强调即时有效治疗起始重要性的治疗指南做出了重大贡献。大型登记系统还表明,偏离这些治疗指南并非个别情况,而是普遍现象。因此,仔细分析治疗途径并进行平衡的干预努力对于弥合知识与行动之间的差距至关重要。本文在2022年9月举行的第8届伦敦 - 因斯布鲁克癫痫持续状态和急性癫痫发作学术讨论会上发表。

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