Chang Ying, Jiang Xin, Liu Wei, Zhang Dongfang, Yang Shubao, Zhao Donghai
Jilin Medical University, jilin, 132013, China.
Zygote. 2023 Apr;31(2):101-110. doi: 10.1017/S0967199422000594. Epub 2023 Feb 6.
In recent years, the incidence of teratospermia has been increasing, and it has become a very important factor leading to male infertility. The research on the molecular mechanism of teratospermia is also progressing rapidly. This article briefly summarizes the clinical incidence of teratozoospermia, and makes a retrospective summary of related studies reported in recent years. Specifically discussing the relationship between gene status and spermatozoa, the review aims to provide the basis for the genetic diagnosis and gene therapy of teratozoospermia.
近年来，畸形精子症的发病率一直在上升，它已成为导致男性不育的一个非常重要的因素。对畸形精子症分子机制的研究也在迅速发展。本文简要总结了畸形精子症的临床发病率，并对近年来报道的相关研究进行了回顾性总结。具体讨论了基因状态与精子之间的关系，该综述旨在为畸形精子症的基因诊断和基因治疗提供依据。
