Zimmers Sylvia, Robieux Léonore, Bungener Catherine
Laboratoire de Psychopathologie et Processus de Santé, Université Paris Cité, Boulogne-Billancourt, France.
Laboratoire de Psychopathologie et Processus de Changement, Université Paris 8- IED, Saint-Denis, France.
J Geriatr Psychiatry Neurol. 2023 Sep;36(5):351-365. doi: 10.1177/08919887231154932. Epub 2023 Feb 5.
Pain is very prevalent in Parkinson's and challenging to manage. As many people with Parkinson's (PwP) with pain suffer from anxious and depressive symptoms, we examined the role of catastrophizing in mediating the relationship between pain and psychological distress for this population.
169 international PwP completed an online survey with socio-demographic and medical data. Participants completed psychometric tests to assess their pain (King's Parkinson's Disease Pain Questionnaire, McGill Pain Questionnaire and Brief Pain Inventory), psychological distress (Beck Depression Inventory and Parkinson Anxiety Scale), pain coping strategies (Coping Strategies Questionnaire) and pain catastrophizing (Pain Catastrophizing Scale).
Depending on the tool used, 82.8% to 95.2% of participants reported pain. 23.5 % and 67.5% of participants showed respectively significant levels of depressive and anxiety symptoms. Psychological distress was significantly correlated with the quality of pain (both sensory and affective dimensions). Statistical models highlighted the mediating role of catastrophizing in the relationship between psychological distress and pain in Parkinson's.
These findings offer new perspectives toward understanding the underlying mechanisms of pain in Parkinson's and for effective therapeutic intervention goals to facilitate adaptation to pain symptoms in Parkinson's.
疼痛在帕金森病中非常普遍且难以管理。由于许多帕金森病患者伴有疼痛，同时还患有焦虑和抑郁症状，我们研究了灾难化思维在介导该人群疼痛与心理困扰之间关系中的作用。
169名来自不同国家的帕金森病患者完成了一项包含社会人口统计学和医学数据的在线调查。参与者完成了心理测量测试，以评估他们的疼痛（国王帕金森病疼痛问卷、麦吉尔疼痛问卷和简明疼痛量表）、心理困扰（贝克抑郁量表和帕金森焦虑量表）、疼痛应对策略（应对策略问卷）和疼痛灾难化思维（疼痛灾难化量表）。
根据所使用的工具，82.8%至95.2%的参与者报告有疼痛。23.5%和67.5%的参与者分别表现出显著水平的抑郁和焦虑症状。心理困扰与疼痛质量（感觉和情感维度）显著相关。统计模型突出了灾难化思维在帕金森病心理困扰与疼痛关系中的中介作用。
这些发现为理解帕金森病疼痛的潜在机制以及实现有效治疗干预目标以促进适应帕金森病疼痛症状提供了新的视角。
