Kong K M, Johnson W F, Anderson P O, Sato L A, Simonian R I
University of California at San Diego Medical Center.
Am J Hosp Pharm. 1987 Sep;44(9):2068-73.
A program developed by the University of California at San Diego Medical Center to curb over-prescribing of cimetidine is described. Guidelines for cimetidine use were approved in September 1985. Pharmacists undertook physician education and enforced the guidelines by monitoring patients through a specially designed documentation form. When use of cimetidine was not in compliance with the guidelines, the pharmacists contacted the physicians to recommend changes. Use of cimetidine hydrochloride injection declined 49% between September 30 and December 6, 1985. Extrapolated to an entire year, this reduction would result in cost savings of +12,000 to +16,000. However, after pharmacists stopped enforcing the guidelines in December 1985, use of cimetidine hydrochloride injection gradually increased to near control levels. In February 1986, the review of patients receiving cimetidine was reinstituted, resulting in another decline in use. Periodic review and reinforcement by pharmacists appear necessary to ensure that cimetidine continues to be prescribed appropriately.
本文描述了由加利福尼亚大学圣地亚哥分校医学中心开发的一项旨在遏制西咪替丁过度处方的项目。西咪替丁使用指南于1985年9月获批。药剂师开展了医师教育工作，并通过一份专门设计的记录表格对患者进行监测，以执行这些指南。当西咪替丁的使用不符合指南时，药剂师会联系医师建议其做出更改。1985年9月30日至12月6日期间，盐酸西咪替丁注射液的使用量下降了49%。 extrapolated to an entire year, this reduction would result in cost savings of +12,000 to +16,000. 然而，在1985年12月药剂师停止执行这些指南后，盐酸西咪替丁注射液的使用量逐渐回升至接近控制水平。1986年2月，对接受西咪替丁治疗的患者的审查工作重新开展，这导致了使用量再次下降。药剂师进行定期审查和强化似乎有必要，以确保西咪替丁继续得到合理处方。
