半规管畸形患者的前庭积水。

Vestibular hydrops in patients with semicircular canal malformation.

机构信息

Eye, Ear, Nose and Throat (EENT) Hospital of Fudan University, Shanghai, China, No. 83, Fenyang Road, Xuhui District, Shanghai, China.

Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China, No. 83, Fenyang Road, Xuhui District, Shanghai, China.

出版信息

Auris Nasus Larynx. 2023 Oct;50(5):727-732. doi: 10.1016/j.anl.2023.01.009. Epub 2023 Feb 4.

DOI:10.1016/j.anl.2023.01.009

PMID:36740469

Abstract

OBJECTIVE

To investigate the vestibular endolymphatic hydrops in patients with semicircular canal malformation.

METHODS

We searched 7864 patients who underwent MR Imaging after contrast injection and found 21 patients with semicircular canal malformations. Another 9 non-malformed patients with unilateral hearing loss were randomly included. We asked patients about their medical history and measured the volume of total vestibular fluid space and endolymphatic space. The vestibular volume ratio = endolymphatic space/total fluid space × 100.

RESULTS

Hearing loss was observed in 18 of 30 malformed ears and in 7 of 12 non-malformed ears. Statistical analysis showed no association between semicircular canal malformation and hearing loss. In the semicircular canal malformation group, the average vestibular volume ratio (22.6%) in the ears with hearing loss was higher than that in the ears without hearing loss (11.4%). There was no statistically significant difference in the average vestibular %EL in ears with hearing loss between the malformed inner ear group (22.6%) and non-malformed group (28.2%) (P>0.05).

CONCLUSION

There was no correlation between semicircular canal malformation and hearing loss. The mean vestibular hydrops volume ratio of the semicircular canal deformed ears with hearing loss was about 22.6%, which was not different from that of normal ears.

摘要

目的

研究半规管畸形患者的前庭内淋巴积水。

方法

我们搜索了 7864 名接受对比剂注射后磁共振成像的患者，发现 21 名患者存在半规管畸形。另外随机纳入 9 名单侧听力损失但无畸形的患者。我们询问了患者的病史，并测量了总前庭液腔和内淋巴液腔的体积。前庭体积比=内淋巴液腔/总液腔×100。

结果

30 个畸形耳中有 18 个出现听力损失，12 个非畸形耳中有 7 个出现听力损失。统计分析显示，半规管畸形与听力损失之间无相关性。在半规管畸形组中，有听力损失的耳的平均前庭体积比（22.6%）高于无听力损失的耳（11.4%）。有听力损失的畸形内耳组（22.6%）与非畸形组（28.2%）的平均前庭内淋巴%EL 无统计学差异（P>0.05）。