• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于深度学习的颈椎后纵韧带骨化术后并发症预测模型

Deep learning-based prediction model for postoperative complications of cervical posterior longitudinal ligament ossification.

机构信息

Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa Ward, Nagoya, Aichi, 466-8550, Japan.

Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo, Japan.

出版信息

Eur Spine J. 2023 Nov;32(11):3797-3806. doi: 10.1007/s00586-023-07562-2. Epub 2023 Feb 6.

DOI:10.1007/s00586-023-07562-2
PMID:36740608
Abstract

PURPOSE

Postoperative complication prediction helps surgeons to inform and manage patient expectations. Deep learning, a model that finds patterns in large samples of data, outperform traditional statistical methods in making predictions. This study aimed to create a deep learning-based model (DLM) to predict postoperative complications in patients with cervical ossification of the posterior longitudinal ligament (OPLL).

METHODS

This prospective multicenter study was conducted by the 28 institutions, and 478 patients were included in the analysis. Deep learning was used to create two predictive models of the overall postoperative complications and neurological complications, one of the major complications. These models were constructed by learning the patient's preoperative background, clinical symptoms, surgical procedures, and imaging findings. These logistic regression models were also created, and these accuracies were compared with those of the DLM.

RESULTS

Overall complications were observed in 127 cases (26.6%). The accuracy of the DLM was 74.6 ± 3.7% for predicting the overall occurrence of complications, which was comparable to that of the logistic regression (74.1%). Neurological complications were observed in 48 cases (10.0%), and the accuracy of the DLM was 91.7 ± 3.5%, which was higher than that of the logistic regression (90.1%).

CONCLUSION

A new algorithm using deep learning was able to predict complications after cervical OPLL surgery. This model was well calibrated, with prediction accuracy comparable to that of regression models. The accuracy remained high even for predicting only neurological complications, for which the case number is limited compared to conventional statistical methods.

摘要

目的

术后并发症预测有助于外科医生告知并管理患者的预期。深度学习是一种在大量数据样本中寻找模式的模型,在预测方面优于传统的统计方法。本研究旨在创建一种基于深度学习的模型(DLM),以预测颈椎后纵韧带骨化(OPLL)患者的术后并发症。

方法

这是一项由 28 家机构进行的前瞻性多中心研究,共纳入 478 例患者进行分析。深度学习用于创建总体术后并发症和神经并发症(主要并发症之一)的两种预测模型。这些模型通过学习患者的术前背景、临床症状、手术过程和影像学表现来构建。还创建了这些逻辑回归模型,并比较了这些模型与 DLM 的准确性。

结果

共有 127 例(26.6%)发生总体并发症。DLM 预测总体并发症发生的准确率为 74.6±3.7%,与逻辑回归相当(74.1%)。发生神经并发症 48 例(10.0%),DLM 的准确率为 91.7±3.5%,高于逻辑回归(90.1%)。

结论

一种使用深度学习的新算法能够预测颈椎 OPLL 手术后的并发症。该模型具有良好的校准能力,预测准确性与回归模型相当。即使仅预测神经并发症,其准确性也很高,与传统的统计方法相比,神经并发症的病例数量有限。

相似文献

1
Deep learning-based prediction model for postoperative complications of cervical posterior longitudinal ligament ossification.基于深度学习的颈椎后纵韧带骨化术后并发症预测模型
Eur Spine J. 2023 Nov;32(11):3797-3806. doi: 10.1007/s00586-023-07562-2. Epub 2023 Feb 6.
2
Could Machine Learning Better Predict Postoperative C5 Palsy of Cervical Ossification of the Posterior Longitudinal Ligament?机器学习能否更好地预测颈椎后纵韧带骨化术后 C5 瘫痪?
Clin Spine Surg. 2022 Jun 1;35(5):E419-E425. doi: 10.1097/BSD.0000000000001295. Epub 2022 Jan 12.
3
The impact of dynamic factors on surgical outcomes after double-door laminoplasty for ossification of the posterior longitudinal ligament of the cervical spine.动态因素对颈椎后纵韧带骨化症双开门椎板成形术后手术效果的影响
J Neurosurg Spine. 2014 Dec;21(6):938-43. doi: 10.3171/2014.8.SPINE131197. Epub 2014 Oct 3.
4
Surgical results and complications of anterior decompression and fusion as a revision surgery after initial posterior surgery for cervical myelopathy due to ossification of the posterior longitudinal ligament.作为后纵韧带骨化所致脊髓型颈椎病初次后路手术后翻修手术的前路减压融合术的手术结果及并发症
J Neurosurg Spine. 2017 Apr;26(4):466-473. doi: 10.3171/2016.9.SPINE16430. Epub 2017 Jan 27.
5
The relationship between preoperative cervical sagittal balance and clinical outcome of laminoplasty treated cervical ossification of the posterior longitudinal ligament patients.术前颈椎矢状平衡与后路颈椎后纵韧带骨化症患者接受椎板成形术治疗的临床疗效的关系。
Spine J. 2020 Sep;20(9):1422-1429. doi: 10.1016/j.spinee.2020.05.542. Epub 2020 May 28.
6
To infer the probability of cervical ossification of the posterior longitudinal ligament and explore its impact on cervical surgery.推断颈椎后纵韧带骨化的概率,并探讨其对颈椎手术的影响。
Sci Rep. 2023 Jun 17;13(1):9816. doi: 10.1038/s41598-023-36992-7.
7
Prospective Investigation of Postoperative Complications in Anterior Decompression with Fusion for Severe Cervical Ossification of the Posterior Longitudinal Ligament: A Multi-institutional Study.严重后纵韧带骨化症行前路减压融合术后并发症的前瞻性研究:多中心研究。
Spine (Phila Pa 1976). 2021 Dec 1;46(23):1621-1629. doi: 10.1097/BRS.0000000000004088.
8
Factors Associated With Loss of Cervical Lordosis After Laminoplasty for Patients With Cervical Ossification of the Posterior Longitudinal Ligament: Data From a Prospective Multicenter Study.颈椎后纵韧带骨化症患者后路单开门椎管扩大成形术后颈椎前凸丢失的相关因素:一项前瞻性多中心研究的数据。
Spine (Phila Pa 1976). 2023 Aug 1;48(15):1047-1056. doi: 10.1097/BRS.0000000000004706. Epub 2023 May 5.
9
Analysis of demographics, risk factors, clinical presentation, and surgical treatment modalities for the ossified posterior longitudinal ligament.骨化型后纵韧带的人口统计学、危险因素、临床表现和手术治疗方式分析。
Neurosurg Focus. 2011 Mar;30(3):E11. doi: 10.3171/2010.12.FOCUS10265.
10
Are clinical outcomes affected by laminoplasty method and K-line in patients with cervical ossification of posterior longitudinal ligament? A multicenter study.颈椎后纵韧带骨化症患者的椎板成形术方式和 K 线与临床疗效的相关性:一项多中心研究。
J Orthop Surg Res. 2022 Nov 24;17(1):513. doi: 10.1186/s13018-022-03407-8.

引用本文的文献

1
Predicting Postoperative Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine Using Interpretable Radiomics Models.使用可解释的放射组学模型预测颈椎后纵韧带骨化的术后进展
Neurospine. 2025 Mar;22(1):144-156. doi: 10.14245/ns.2448846.423. Epub 2025 Mar 31.
2
Deep learning for identifying cervical ossification of the posterior longitudinal ligament: a systematic review and meta-analysis.深度学习用于识别后纵韧带骨化:一项系统评价和荟萃分析。
Quant Imaging Med Surg. 2025 Mar 3;15(3):1719-1740. doi: 10.21037/qims-24-1485. Epub 2025 Feb 26.
3
A deep learning-based prediction model for prognosis of cervical spine injury: a Japanese multicenter survey.

本文引用的文献

1
Factors Significantly Associated with Postoperative Neck Pain Deterioration after Surgery for Cervical Ossification of the Posterior Longitudinal Ligament: Study of a Cohort Using a Prospective Registry.与后纵韧带骨化症手术后颈部疼痛恶化显著相关的因素:一项使用前瞻性登记的队列研究
J Clin Med. 2021 Oct 28;10(21):5026. doi: 10.3390/jcm10215026.
2
Minimally invasive multiple-rod constructs with robotics planning in adult spinal deformity surgery: a case series.成人脊柱畸形手术中基于机器人规划的微创多棒结构:病例系列
Eur Spine J. 2022 Jan;31(1):95-103. doi: 10.1007/s00586-021-06980-4. Epub 2021 Oct 1.
3
Risk factors for surgical complications in the management of ossification of the posterior longitudinal ligament.
基于深度学习的颈椎损伤预后预测模型:一项日本多中心调查。
Eur Spine J. 2025 Feb 10. doi: 10.1007/s00586-025-08708-0.
4
Performance and clinical implications of machine learning models for detecting cervical ossification of the posterior longitudinal ligament: a systematic review.用于检测后纵韧带骨化的机器学习模型的性能及临床意义:一项系统评价
Asian Spine J. 2025 Feb;19(1):148-159. doi: 10.31616/asj.2024.0452. Epub 2025 Jan 20.
5
Application and Prospects of Deep Learning Technology in Fracture Diagnosis.深度学习技术在骨折诊断中的应用与前景
Curr Med Sci. 2024 Dec;44(6):1132-1140. doi: 10.1007/s11596-024-2928-5. Epub 2024 Nov 18.
后纵韧带骨化症手术并发症的危险因素。
Spine J. 2021 Jul;21(7):1176-1184. doi: 10.1016/j.spinee.2021.03.022. Epub 2021 Mar 26.
4
Development of a Novel, Potentially Universal Machine Learning Algorithm for Prediction of Complications After Total Hip Arthroplasty.开发一种用于预测全髋关节置换术后并发症的新型、可能通用的机器学习算法。
J Arthroplasty. 2021 May;36(5):1655-1662.e1. doi: 10.1016/j.arth.2020.12.040. Epub 2020 Dec 30.
5
Potential Biases in Machine Learning Algorithms Using Electronic Health Record Data.利用电子健康记录数据的机器学习算法中的潜在偏差。
JAMA Intern Med. 2018 Nov 1;178(11):1544-1547. doi: 10.1001/jamainternmed.2018.3763.
6
Timing of complications following posterior cervical fusion.颈椎后路融合术后并发症的发生时间。
J Orthop. 2018 Mar 31;15(2):522-526. doi: 10.1016/j.jor.2018.03.010. eCollection 2018 Jun.
7
Guidelines for Developing and Reporting Machine Learning Predictive Models in Biomedical Research: A Multidisciplinary View.生物医学研究中机器学习预测模型开发与报告指南:多学科视角
J Med Internet Res. 2016 Dec 16;18(12):e323. doi: 10.2196/jmir.5870.
8
Prevalence, Concomitance, and Distribution of Ossification of the Spinal Ligaments: Results of Whole Spine CT Scans in 1500 Japanese Patients.脊柱韧带骨化的患病率、伴发情况及分布:1500例日本患者全脊柱CT扫描结果
Spine (Phila Pa 1976). 2016 Nov 1;41(21):1668-1676. doi: 10.1097/BRS.0000000000001643.
9
Prevalence of C5 nerve root palsy after cervical decompressive surgery: a meta-analysis.颈椎减压手术后C5神经根麻痹的患病率:一项荟萃分析。
Eur Spine J. 2015 Dec;24(12):2724-34. doi: 10.1007/s00586-015-4186-5. Epub 2015 Aug 18.
10
Deep learning.深度学习。
Nature. 2015 May 28;521(7553):436-44. doi: 10.1038/nature14539.