Altered elimination of desmethyldiazepam in the elderly.
作者信息
Klotz U, Müller-Seydlitz P
出版信息
Br J Clin Pharmacol. 1979 Jan;7(1):119-20. doi: 10.1111/j.1365-2125.1979.tb00908.x.
Abstract
摘要
相似文献
1
Altered elimination of desmethyldiazepam in the elderly.老年人去甲基地西泮清除率的改变。
Br J Clin Pharmacol. 1979 Jan;7(1):119-20. doi: 10.1111/j.1365-2125.1979.tb00908.x.
2
Elimination kinetics of desmethyldiazepam in two young and two elderly subjects.
Eur J Drug Metab Pharmacokinet. 1982 Jan-Mar;7(1):69-72. doi: 10.1007/BF03189546.
3
Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam.
Eur J Clin Pharmacol. 1980 Nov;18(6):517-20. doi: 10.1007/BF00874666.
4
Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration.地西泮给药后地西泮及其主要代谢产物去甲地西泮的药代动力学模型。
J Pharm Sci. 1983 Nov;72(11):1318-23. doi: 10.1002/jps.2600721120.
5
Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).肥胖导致药物半衰期延长：去甲基地西泮（氯氮卓）的研究。
J Pharm Sci. 1982 Aug;71(8):942-4. doi: 10.1002/jps.2600710827.
6
Elimination half-life of nordiazepam.去甲西泮的消除半衰期。
South Med J. 1979 Jun;72(6):769-70. doi: 10.1097/00007611-197906000-00047.
7
The pharmacokinetics of diazepam and desmethyldiazepam in rat brain and plasma.地西泮和去甲基地西泮在大鼠脑和血浆中的药代动力学。
Psychopharmacology (Berl). 1986;88(3):267-70. doi: 10.1007/BF00180822.
8
Desmethyldiazepam kinetics in the elderly after oral prazepam.老年人口服普拉西泮后去甲基地西泮的动力学
Clin Pharmacol Ther. 1980 Aug;28(2):196-202. doi: 10.1038/clpt.1980.150.
9
Comparative protein binding of diazepam and desmethyldiazepam.地西泮和去甲基地西泮的蛋白质结合比较
J Clin Pharmacol. 1980 Nov-Dec;20(11):639-43. doi: 10.1002/j.1552-4604.1980.tb01680.x.
10
[Clinical pharmacokinetics of diazepam and its biologically active metabolites (author's transl)].
Klin Wochenschr. 1978 Sep 15;56(18):895-904. doi: 10.1007/BF01489215.
引用本文的文献
1
Managing alcohol withdrawal in the elderly.老年人酒精戒断的管理
Drugs Aging. 1999 Jun;14(6):409-25. doi: 10.2165/00002512-199914060-00002.
2
Effect of age and liver cirrhosis on the pharmacokinetics of nitrazepam.年龄和肝硬化对硝西泮药代动力学的影响。
Br J Clin Pharmacol. 1983 Mar;15(3):295-302. doi: 10.1111/j.1365-2125.1983.tb01502.x.
3
Pinazepam: a precursor of N-desmethyldiazepam.匹那西泮：N-去甲基地西泮的前体。
Eur J Clin Pharmacol. 1982;22(3):225-8. doi: 10.1007/BF00545219.
4
Elimination kinetics of desmethyldiazepam in two young and two elderly subjects.
Eur J Drug Metab Pharmacokinet. 1982 Jan-Mar;7(1):69-72. doi: 10.1007/BF03189546.
5
Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam.
Eur J Clin Pharmacol. 1980 Nov;18(6):517-20. doi: 10.1007/BF00874666.
6
Pharmacokinetics of brotizolam in the elderly.溴替唑仑在老年人中的药代动力学。
Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):299S-307S. doi: 10.1111/j.1365-2125.1983.tb02304.x.
7
[Benzodiazepines: significance of kinetics for therapy].[苯二氮䓬类药物：动力学在治疗中的意义]
Klin Wochenschr. 1983 Mar 1;61(5):213-24. doi: 10.1007/BF01496127.
8
Clobazam kinetics in the elderly.老年人中氯巴占的动力学
Br J Clin Pharmacol. 1981 Nov;12(5):631-6. doi: 10.1111/j.1365-2125.1981.tb01281.x.
9
Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate.年龄和性别对由其前体氯氮䓬形成的去甲基地西泮处置的影响。
Psychopharmacology (Berl). 1981;75(2):193-7. doi: 10.1007/BF00432186.
10
Benzodiazepines: clinical pharmacology and therapeutic use.苯二氮䓬类药物：临床药理学与治疗用途。
Drugs. 1980 Mar;19(3):195-219. doi: 10.2165/00003495-198019030-00004.
本文引用的文献
1
Metabolism of diazepam in rat, dog, and man.地西泮在大鼠、狗和人体内的代谢
J Pharmacol Exp Ther. 1965 Sep;149(3):423-35.
2
Time integral of drug concentration in the central (plasma) compartment.中央（血浆）室药物浓度的时间积分。
J Pharm Sci. 1970 May;59(5):722-3. doi: 10.1002/jps.2600590537.
3
Pharmacology of the metabolites of chlordiazepoxide and diazepam.
Curr Ther Res Clin Exp. 1965 Sep;7(9):590-606.
4
The effects of age and liver disease on the disposition and elimination of diazepam in adult man.年龄和肝脏疾病对成年男性体内地西泮处置与消除的影响。
J Clin Invest. 1975 Feb;55(2):347-59. doi: 10.1172/JCI107938.
5
Comparison of the pharmacokinetics of diazepam after single and subchronic doses.单次和亚慢性剂量后地西泮的药代动力学比较。
Eur J Clin Pharmacol. 1976 Jun 15;10(2):121-6. doi: 10.1007/BF00609470.
6
Absorption and disposition of chlordiazepoxide in young and elderly male volunteers.
J Clin Pharmacol. 1977 Nov-Dec;17(11-12):709-18. doi: 10.1002/j.1552-4604.1977.tb01546.x.
7
Normal disposition of oxazepam in acute viral hepatitis and cirrhosis.
Ann Intern Med. 1976 Apr;84(4):420-5. doi: 10.7326/0003-4819-84-4-420.
8
Effect of age and parenchymal liver disease on the disposition and elimination of chlordiazepoxide (librium).
Gastroenterology. 1978 Sep;75(3):479-85.
9
Effects of aging and liver disease on disposition of lorazepam.
Clin Pharmacol Ther. 1978 Oct;24(4):411-9. doi: 10.1002/cpt1978244411.
Zotero 插件