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用于经股骨截肢者的采用压配式骨整合的翻修截肢术

Revision Amputation with Press-Fit Osseointegration for Transfemoral Amputees.

作者信息

Hoellwarth Jason S, Reif Taylor J, Rozbruch S Robert

机构信息

Limb Lengthening and Complex Reconstruction Service, Osseointegration Limb Replacement Center, Hospital for Special Surgery, New York, NY.

出版信息

JBJS Essent Surg Tech. 2022 Jun 1;12(2). doi: 10.2106/JBJS.ST.21.00068. eCollection 2022 Apr-Jun.

DOI:10.2106/JBJS.ST.21.00068
PMID:36741033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9889284/
Abstract

UNLABELLED

Press-fit transfemoral osseointegration is the technique of inserting an intramedullary metal implant into the residual femur of an amputee; the implant is passed transcutaneously to attach to a standard prosthesis that includes a knee, tibia, ankle, and foot. This allows the prosthesis to be skeletally anchored, eliminating socket-related problems such as tissue compression that can provoke neurogenic pain, skin abrasion, and fitting problems resulting from residual limb size fluctuation. Amputees with osseointegrated prostheses typically wear their prosthesis more and experience better mobility, quality of life, and extremity proprioception compared to those with socket prostheses.

DESCRIPTION

We demonstrate the fundamentals of a single-stage procedure involving an impacted press-fit porous-coated titanium osseointegration implant. The preoperative evaluation is summarized and the specific surgical steps are described: exposure, osteotomy, canal preparation, implant insertion, (optional) targeted muscle reinnervation, muscle closure, soft-tissue contouring and stoma creation, and abutment insertion.

ALTERNATIVES

Amputees who are dissatisfied with their quality of life or mobility when using a socket prosthesis can attempt to modify their socket or activity level or accept their situation. Non-osseointegration surgical options to try to improve socket fit include bone lengthening and/or soft-tissue contouring. An alternative design is a screw-type osseointegration implant.

RATIONALE

Press-fit osseointegration can be provided for amputees having difficulty with socket wear. Press-fit osseointegration usually provides superior mobility and quality of life compared with nonoperative and other operative options for patients expressing dissatisfaction for reasons such as those mentioned above, including poor fit, compromised energy transfer, skin pinching, compression, and abrasions.

EXPECTED OUTCOMES

Review articles describing the clinical outcomes of osseointegration consistently suggest that patients have improved prosthesis wear time, mobility, and quality of life compared with patients with a socket prosthesis. In a recent study of 18 femoral and 13 tibial amputees who had osseointegration, Reif et al. showed significant improvements in prosthesis wear time, mobility, and multiple quality-of-life surveys at a mean follow-up of nearly 2 years. The most common postoperative complication for this procedure is low-grade soft-tissue infection, which is usually managed by a short course of oral antibiotics. Much less often, soft-tissue debridement or implant removal may be needed to manage infection. Periprosthetic fractures can nearly always be managed with familiar fracture fixation techniques and implant retention.

IMPORTANT TIPS

Template and choose an implant with an optimal diameter that encroaches the inner cortex at the narrowest bone diameter; an implant that is too wide may not fit without causing a large fracture, and an implant that is too narrow may fall out. Do not cement the implant.Ideally, the abutment of the implant should rest against a flat transverse bone end with cortical contact and leave the correct amount of room for the prosthetic knee so that it matches the height of the contralateral knee; avoid inserting an implant too distally or in too wide a metaphyseal flare.Gentle impaction pressure is necessary and small contained distal fractures are acceptable, but avoid causing a propagating fracture. Do not place cerclage cables or loose bone graft at these small fracture sites.Avoid the use of a tourniquet during intramedullary reaming to prevent potential heat-induced osteonecrosis.Nerve surgery such as targeted muscle reinnervation, if indicated, can be performed in the same surgical episode as the osseointegration.The muscles should be closed at the bone-implant interface with use of a tight purse string in order to provide a vascularized tissue barrier against bacterial ingress.The skin surrounding the stoma should have unnecessary fat removed, but not excess removal leading to skin necrosis. The skin fascia should be sutured to the muscle surrounding the stoma to stabilize the peri-stomal skin.Soft-tissue contouring is needed to achieve the optimal soft-tissue tension around the stoma and abutment. Single-stage surgery has a distinct advantage in this regard.

ACRONYMS AND ABBREVIATIONS

MVA = motor vehicle accidentAP = anteroposteriorCT = computed tomographyTMR = targeted muscle reinnervationQTFA = Questionnaire for Persons with a Transfemoral AmputationEQ-5D = EuroQol 5 DimensionsLD-SRS = Limb Deformity-Scoliosis Research Society (questionnaire)PROMIS = Patient-Reported Outcomes Measurement Information System.

摘要

未标注

压配式经股骨骨整合是将髓内金属植入物插入截肢者残留股骨的技术;植入物经皮穿出,与包括膝关节、胫骨、踝关节和足部的标准假体相连。这使得假体能够骨骼锚固,消除与承窝相关的问题,如可能引发神经源性疼痛、皮肤磨损以及因残肢尺寸波动导致的适配问题。与使用承窝式假体的截肢者相比,使用骨整合假体的截肢者通常佩戴假体的时间更长,并且在行动能力、生活质量和肢体本体感觉方面表现更佳。

描述

我们展示了一种涉及冲击式压配多孔涂层钛骨整合植入物的单阶段手术的基本原理。总结了术前评估并描述了具体手术步骤:暴露、截骨、髓腔准备、植入物插入、(可选)靶向肌肉再支配、肌肉闭合、软组织塑形和造口创建以及基台插入。

替代方案

对使用承窝式假体时生活质量或行动能力不满意的截肢者,可以尝试修改承窝或活动水平,或者接受现状。为改善承窝适配而尝试的非骨整合手术选项包括骨延长和/或软组织塑形。另一种设计是螺旋式骨整合植入物。

原理

对于佩戴承窝有困难的截肢者,可以采用压配式骨整合。与因上述原因(如适配不佳、能量传递受损、皮肤挤压、压迫和磨损)而表示不满的患者的非手术和其他手术选项相比,压配式骨整合通常能提供更好的行动能力和生活质量。

预期结果

描述骨整合临床结果的综述文章一致表明,与使用承窝式假体的患者相比,患者的假体佩戴时间、行动能力和生活质量有所改善。在最近一项对18名股骨截肢者和13名胫骨截肢者进行骨整合的研究中,赖夫等人显示,在平均近2年的随访中,假体佩戴时间、行动能力以及多项生活质量调查都有显著改善。该手术最常见的术后并发症是轻度软组织感染,通常通过短期口服抗生素治疗。很少情况下,可能需要进行软组织清创或取出植入物来控制感染。假体周围骨折几乎总能通过熟悉的骨折固定技术和保留植入物来处理。

重要提示

使用模板并选择直径最佳的植入物,使其在最窄的骨直径处侵入内皮质;过宽的植入物可能无法适配且会导致大骨折,过窄的植入物可能会脱落。不要用骨水泥固定植入物。理想情况下,植入物的基台应靠在平坦的横向骨端并与皮质接触,为假体膝关节留出正确的空间,使其与对侧膝关节高度匹配;避免植入物插入过远或在干骺端扩大部分过宽。轻柔的冲击压力是必要的,小的局限性远端骨折是可以接受的,但要避免造成骨折扩展。不要在这些小骨折部位放置环扎钢丝或松散的骨移植材料。在髓腔扩孔时避免使用止血带,以防止潜在的热诱导骨坏死。如有指征,如靶向肌肉再支配等神经手术可在与骨整合相同的手术过程中进行。应使用紧密的荷包缝合在骨 - 植入物界面处闭合肌肉,以提供防止细菌侵入的血管化组织屏障。造口周围的皮肤应去除不必要的脂肪,但不要过度去除导致皮肤坏死。皮肤筋膜应缝合到造口周围的肌肉上,以稳定造口周围皮肤。需要进行软组织塑形以在造口和基台周围实现最佳的软组织张力。单阶段手术在这方面具有明显优势。

首字母缩略词和缩写

MVA = 机动车事故;AP = 前后位;CT = 计算机断层扫描;TMR = 靶向肌肉再支配;QTFA = 经股骨截肢者问卷;EQ - 5D = 欧洲五维健康量表;LD - SRS = 肢体畸形 - 脊柱侧弯研究协会(问卷);PROMIS = 患者报告结果测量信息系统

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