van Helmond Jennifer L, Fitts Brittany, Chauhan Jigar C
Department of Pediatrics, Division of Critical Care Medicine, Nemours/Alfred I. duPont Hospital for Children, Delaware, United States.
Department of Pediatrics, Sidney Kimmel Medical College, Thomas Jefferson University, Pennsylvania, United States.
J Pediatr Intensive Care. 2021 May 18;12(1):12-17. doi: 10.1055/s-0041-1727249. eCollection 2023 Mar.
The coronavirus disease 2019 (COVID-19) pandemic and related community mitigation measures had a significant psychosocial impact. We suspected that more patients were admitted to our pediatric intensive care unit (PICU) for toxic ingestions since the start of the pandemic. We therefore investigated if PICU admissions related to toxic ingestions were higher in 2020 as a result of COVID-19 compared with previous years. We completed a cross-sectional study at a tertiary children's hospital comparing admissions to our PICU between April 2020 and October 2020, during which COVID-19 and community mitigation measures were in place, to those during the same 7-month period in the previous 3 years. Total PICU admissions, admissions for all toxic ingestions (intentional ingestions and accidental ingestions), and demographic and clinical characteristics of patients were compared. Total PICU admissions in 2020 during COVID-19 pandemic months were lower compared with the same months in the preceding 3 years (-16%, < 0.001), however, admissions for toxic ingestions were higher during COVID-19 (+64%, < 0.001). When separated by type, intentional (+55%, = 0.012) and accidental ingestions (+94%, = 0.021) were higher during COVID-19. COVID-19 with community mitigation measures has led to an increase in PICU admissions for intentional and accidental ingestions, indicating an increase in severity of toxic ingestions in children associated with the pandemic. Mental health of adolescents, and safety of infants and toddlers in their home environment, should be targeted with specific interventions in the ongoing COVID-19 pandemic.
2019年冠状病毒病（COVID-19）大流行及相关社区缓解措施产生了重大的社会心理影响。我们怀疑自大流行开始以来，有更多因有毒物质摄入而入住我们儿科重症监护病房（PICU）的患者。因此，我们调查了与前几年相比，2020年因COVID-19导致的与有毒物质摄入相关的PICU入院人数是否更高。我们在一家三级儿童医院完成了一项横断面研究，比较了2020年4月至2020年10月期间（在此期间实施了COVID-19及社区缓解措施）与前三年相同7个月期间入住我们PICU的情况。比较了PICU总入院人数、所有有毒物质摄入（故意摄入和意外摄入）的入院人数以及患者的人口统计学和临床特征。与前三年的同月相比，2020年COVID-19大流行期间PICU总入院人数较低（-16%，<0.001），然而，COVID-19期间有毒物质摄入的入院人数较高（+64%，<0.001）。按类型分开时，COVID-19期间故意摄入（+55%，P = 0.012）和意外摄入（+94%，P = 0.021）均较高。COVID-19及社区缓解措施导致PICU因故意和意外摄入的入院人数增加，表明与大流行相关的儿童有毒物质摄入的严重程度增加。在持续的COVID-19大流行中，应针对青少年的心理健康以及婴幼儿在家中环境的安全采取具体干预措施。
