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一项针对乳腺癌患者炎症因子、负性情绪及生活质量的心理护理干预措施。

A Psychological Nursing Intervention for Patients with Breast Cancer on Inflammatory Factors, Negative Emotions and Quality of Life.

作者信息

Li Mo, Xie Xianxin, Xu Hui, Li Hui

机构信息

Department of Breast Surgery, Cancer Hospital of China Medical University, Shenyang 110042, Liaoning Province, China.

出版信息

Iran J Public Health. 2022 Sep;51(9):2041-2047. doi: 10.18502/ijph.v51i9.10559.

DOI:10.18502/ijph.v51i9.10559
PMID:36743364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9884377/
Abstract

BACKGROUND

We aimed to evaluate the effect of a psychological nursing intervention on inflammatory factors, negative emotions and quality of life in patients with breast cancer.

METHODS

Patients at the Cancer Hospital of China Medical University from January 2017 to January 2020 were stratified into two groups based on the way of nursing. Patients in the control group received routine care, and the experimental group received appropriate psychological care interventions in addition to routine care. We compared the inflammatory factors (interleukin-6 (IL-6) and C reactive protein (CRP)), negative emotions (self-rating depression scale (SDS) and self-rating anxiety scale (SAS)) and quality of Life (short form-36 survey (SF-36)) between two groups.

RESULTS

A total of 226 patients with breast cancer were enrolled in this study. Before the intervention, the CRP, IL-6, SAS and SDS between two groups were not significantly different (=0.205, 0.971, 0.590, 1.579; =0.838, 0.332, 0.556, 0.116). After the intervention, the CRP, IL-6, SAS and SDS between two groups were decreased and significantly different (=-17.648, -18.079, -18.267, -18.613; <0.05) Besides, the social function , physiological function, mental health, physical pain, physical limitation, vitality, emotional functions and overall health were improved and significantly different between two groups after intervention (<0.05).

CONCLUSION

A psychological nursing Intervention has the beneficial effect on the inflammatory factors, negative emotions and quality of life in patients with breast cancer.

摘要

背景

我们旨在评估心理护理干预对乳腺癌患者炎症因子、负面情绪和生活质量的影响。

方法

将2017年1月至2020年1月在中国医科大学附属肿瘤医院就诊的患者按护理方式分为两组。对照组接受常规护理,试验组在常规护理基础上接受适当的心理护理干预。我们比较了两组患者的炎症因子(白细胞介素-6(IL-6)和C反应蛋白(CRP))、负面情绪(自评抑郁量表(SDS)和自评焦虑量表(SAS))及生活质量(36条目简明健康调查量表(SF-36))。

结果

本研究共纳入226例乳腺癌患者。干预前,两组患者的CRP、IL-6、SAS和SDS差异无统计学意义(=0.205, 0.971, 0.590, 1.579;=0.838, 0.332, 0.556, 0.116)。干预后,两组患者的CRP、IL-6、SAS和SDS均降低且差异有统计学意义(=-17.648, -18.079, -18.267, -18.613;<0.05)。此外,干预后两组患者的社会功能、生理功能、心理健康、躯体疼痛、身体功能受限、活力、情感功能和总体健康状况均得到改善且差异有统计学意义(<0.05)。

结论

心理护理干预对乳腺癌患者的炎症因子、负面情绪和生活质量有有益影响。

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