Patel Neehar R, Takwale Anupam B, Mansukhani K A, Jaggi Sunila, Thatte Mukund R
Department of Plastic Surgery, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.
Department of Clinical Neurophysiology, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.
Indian J Plast Surg. 2022 Dec 22;55(4):331-338. doi: 10.1055/s-0042-1760253. eCollection 2022 Dec.
The majority of brachial plexus injuries (BPIs) are caused by trauma; most commonly due to two-wheeler road accidents. It is important to determine whether the lesion in question is pre-ganglionic or post-ganglionic for purposes of surgical planning and prognosis. Diagnostic testing helps the surgeon to not only decide whether surgical intervention is required, but also in planning the procedure, thereby maximizing the patient's chances of early return to function. The aim of the study was to determine the diagnostic efficacy of electrodiagnostic studies (Edx) and magnetic resonance imaging (MRI) individually, and in unison, in detecting the type and site of BPI by comparison with intraoperative findings (which were used as the reference standard) in patients with posttraumatic BPI. It is an observational cross-sectional prospective randomized study, wherein 48 patients with BPI underwent a detailed clinical and neurological examination of the upper limb, Edx, MRI neurography and were subsequently operated upon. We assessed a total of 240 roots. The diagnosis of all spinal roots was noted on Edx. MRI was performed to look for root avulsion, pseudomeningocoele, and/or rupture injury. The patients were subsequently operated upon. All roots were traced from infraclavicular level right up to the foramen to ensure continuity of root or note rupture/ avulsion. The findings were tabulated. MRI accurately diagnosed 138 of the 147 injured roots and MRI sensitivity for the detection of BPI was 93.88%, whereas Edx correctly identified 146 out of 147 injured roots and thus, had sensitivity of 99.32%; however, both lacked specificity (18.28 and 20.43%, respectively). With Edx and MRI in unison, sensitivity was 100% which meant that if a given patient with a BPI is subjected to both tests, not a single abnormal root will go unnoticed. Edx and MRI are two highly sensitive investigation modalities whose combined sensitivity is 100% for the detection of a root injury. Therefore, we recommend both tests as they are excellent screening tests.
大多数臂丛神经损伤(BPI)由创伤引起;最常见于两轮机动车道路交通事故。为了进行手术规划和判断预后,确定所讨论的损伤是节前还是节后损伤很重要。诊断测试不仅有助于外科医生决定是否需要手术干预,还能用于规划手术过程,从而最大程度提高患者早期恢复功能的几率。本研究的目的是通过与创伤后臂丛神经损伤患者的术中发现(用作参考标准)进行比较,分别及联合确定电诊断研究(Edx)和磁共振成像(MRI)在检测臂丛神经损伤的类型和部位方面的诊断效能。
这是一项观察性横断面前瞻性随机研究,其中48例臂丛神经损伤患者接受了上肢详细的临床和神经学检查、Edx、MRI神经成像检查,随后接受手术。我们总共评估了240个神经根。通过Edx记录所有脊神经根的诊断情况。进行MRI检查以寻找神经根撕脱、假性脊膜膨出和/或断裂损伤。随后患者接受手术。从锁骨下水平一直追踪所有神经根直至椎间孔,以确保神经根的连续性或记录断裂/撕脱情况。将结果制成表格。
MRI准确诊断出147条受损神经根中的138条,MRI检测臂丛神经损伤的敏感性为93.88%,而Edx正确识别出147条受损神经根中的146条,因此敏感性为99.32%;然而,两者均缺乏特异性(分别为18.28%和20.43%)。Edx和MRI联合使用时,敏感性为100%,这意味着如果给定的臂丛神经损伤患者同时接受这两项检查,不会有任何一条异常神经根被漏诊。
Edx和MRI是两种高度敏感的检查方式,它们联合检测神经根损伤的敏感性为100%。因此,我们推荐这两项检查,因为它们是优秀的筛查检查。