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新冠疫情大流行的第一年早产情况减少了吗?对2017年至2020年柏林围产期数据的评估

Fewer Preterm Births in the First COVID-19 Pandemic Year? An Evaluation of the Berlin Perinatal Data for the Years 2017 to 2020.

作者信息

David Matthias, Reutter Tilman

机构信息

Klinik für Gynäkologie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.

LAG DeQS Berlin, Berlin, Germany.

出版信息

Geburtshilfe Frauenheilkd. 2023 Feb 3;83(2):184-191. doi: 10.1055/a-1987-5716. eCollection 2023 Feb.

Abstract

The study analyzes and interprets possible effects of the COVID-19 pandemic on the preterm birth rate. Research questions included: were there fewer preterm births in Berlin in 2020, the first year of the pandemic, compared to the three years before the pandemic? Were there differences in preterm birth rates grouped according to weeks of gestation? The perinatal data of all singleton pregnancies were evaluated with regard to birth rates in Berlin, and the numbers of preterm neonates born in the three pre-pandemic years from 2017 to 2019 were compared to the rate for 2020, the first year of the pandemic. The overall number of singleton pregnancies born in maternity hospitals and labor wards in Berlin decreased in the first year of the pandemic. The percentage of preterm neonates born before 37 + 0 weeks of gestation (GW) was significantly lower in 2020 compared to the three previous years, with significantly more preterm neonates born before 28 + 0 GW and significantly fewer preterm neonates born between 28 + 0 to 35 + 0 GW. In 2020, significantly fewer neonates born before 37 + 0 weeks of gestation were delivered by primary caesarean section. The incidence of induced births was approximately the same. In the first year of the pandemic, a range of social, iatrogenic, and biological factors may have had an impact on preterm birth rates. A Germany-wide evaluation of perinatal data across different German federal states for the period 2020 to 2022 would offer the opportunity to identify the causes of this lower rate of preterm births and determine whether conclusions can be drawn from this which would affect future strategies to reduce preterm birth rates.

摘要

该研究分析并解读了新冠疫情对早产率可能产生的影响。研究问题包括:在疫情的第一年即2020年,柏林的早产情况与疫情前三年相比是否有所减少?根据孕周分组的早产率是否存在差异?针对柏林的出生率,对所有单胎妊娠的围产期数据进行了评估,并将2017年至2019年这三个疫情前年份的早产新生儿数量与疫情第一年即2020年的早产率进行了比较。在疫情的第一年,柏林妇产医院和产房出生的单胎妊娠总数有所下降。与前三年相比,2020年妊娠37 + 0周之前出生的早产新生儿百分比显著降低,妊娠28 + 0周之前出生的早产新生儿显著增多,而妊娠28 + 0周至35 + 0周之间出生的早产新生儿显著减少。2020年,妊娠37 + 0周之前出生的新生儿通过初次剖宫产分娩的数量显著减少。引产发生率大致相同。在疫情的第一年,一系列社会、医源性和生物学因素可能对早产率产生了影响。对2020年至2022年期间德国不同联邦州的围产期数据进行全德范围的评估,将有机会确定早产率降低的原因,并判断是否能从中得出影响未来降低早产率策略的结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e52/9897895/3c936e82b333/10-1055-a-1987-5716-i19977853.jpg

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