Lee Ahee, Kim Heegoo, Kim Jinuk, Choi Dong-Sung, Jung Jae Hwan, Lee Jungsoo, Kim Yun-Hee
Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.
Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Brain Neurorehabil. 2020 Mar 26;13(2):e12. doi: 10.12786/bn.2020.13.e12. eCollection 2020 Jul.
Whole-body vibration exercise (WBVe) can provide proper somatosensory stimulation and improve muscle strength in stroke patients. This study investigated the effects of WBVe on gait function and cortical activity in patients with chronic stroke. Thirty stroke patients were randomly assigned to either the WBVe or the control group. The WBVe group received the vibration in a half-squat position for 5 minutes at an intensity of 20 Hz. The control group kept the same posture but did not receive the vibration. Cortical activity was investigated using functional near-infrared spectroscopy (fNIRS). Gait function was assessed by a 10-m walk test (10MWT), a timed up and go (TUG) test, a Fugl-Meyer Assessment, and a Tinetti Performance-Oriented Mobility Assessment (TPOMA). In group analysis of the fNIRS data, oxygenated hemoglobin concentration was significantly increased in the ipsilesional supplementary motor area, bilateral sensorimotor cortex, and contralesional prefrontal cortex in the WBVe group compared to the control group (p < 0.05). Functional assessment demonstrated a significant interaction between time and group for the 10MWT and TUG test, suggesting that the WBVe group demonstrated meaningful improvement after intervention (p < 0.05). These results suggested that WBVe modulated the cerebral cortical activities and resulted in improvement of gait function in chronic stroke patients.
ClinicalTrials.gov Identifier: NCT03375346.
全身振动训练（WBVe）可为中风患者提供适当的体感刺激并增强肌肉力量。本研究调查了WBVe对慢性中风患者步态功能和皮质活动的影响。30名中风患者被随机分为WBVe组或对照组。WBVe组以20赫兹的强度在半蹲姿势下接受5分钟的振动。对照组保持相同姿势但不接受振动。使用功能近红外光谱（fNIRS）研究皮质活动。通过10米步行测试（10MWT）、定时起立行走测试（TUG）、Fugl-Meyer评估和Tinetti以性能为导向的移动性评估（TPOMA）评估步态功能。在fNIRS数据的组分析中，与对照组相比，WBVe组患侧辅助运动区、双侧感觉运动皮层和对侧前额叶皮层的氧合血红蛋白浓度显著增加（p < 0.05）。功能评估表明，10MWT和TUG测试在时间和组之间存在显著交互作用，表明WBVe组在干预后有显著改善（p < 0.05）。这些结果表明，WBVe调节了大脑皮质活动，并导致慢性中风患者的步态功能得到改善。
ClinicalTrials.gov标识符：NCT03375346。
