Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
J Feline Med Surg. 2023 Feb;25(2):1098612X221149348. doi: 10.1177/1098612X221149348.
The aim of this study was to evaluate the use of inhalant anesthesia vs sedation for urinary catheter placement in male cats with urethral obstruction. The primary outcome measures were the incidence of complications related to catheterization, the incidence of recurrent urethral obstruction (rUO; both during hospitalization and within 1 year) and survival. The secondary aim of this study was to evaluate the association between baseline serum biochemical concentrations and antispasmodic medications with complications and short-term rUO.
We carried out a retrospective review of records from a university teaching hospital from 2009 to 2020. Cats were included if diagnosed with a urinary obstruction, based on the presence of a large, painful and non-expressible bladder, a urinary catheter was placed and hospitalization occurred for a minimum of 24 h. Collected baseline data included age, breed, weight, serum biochemical concentrations and if cats underwent sedation or inhalant anesthesia for urethral catheterization. For the comparison of inhalant anesthesia or sedation, univariate logistic regression was used.
There was no statistically significant difference in complications or the recurrence of obstruction in cats with urethral obstruction that underwent inhalant anesthesia compared with sedation. All serum biochemical concentrations were significantly associated with survival. Decreased serum ionized calcium was found to be statistically significantly associated with higher complication rates ( = 0.0086), as well as short-term recurrence of obstruction ( = 0.004). Increased serum potassium concentrations were found to be statistically significantly associated with the risk of short-term recurrent urethral obstruction ( = 0.0345). No significant difference was found between the use of antispasmodic medications with short-term recurrence.
No significant difference was found between complications or recurrence rates when comparing the use of inhalant anesthesia to sedation protocols. Baseline serum biochemical data were significantly associated with complications, survival and short-term recurrence rates.
本研究旨在评估吸入麻醉与镇静在治疗雄性猫尿道梗阻性导尿中的应用。主要结局指标为与导尿相关的并发症发生率、再发性尿道梗阻(rUO;包括住院期间和 1 年内)发生率和生存率。本研究的次要目的是评估基础血清生化浓度和抗痉挛药物与并发症和短期 rUO 的关系。
我们对 2009 年至 2020 年一所大学教学医院的病历进行了回顾性分析。如果猫出现大、痛、不可表达的膀胱,诊断为尿梗阻,并放置导尿管,住院时间至少 24 小时,则纳入本研究。收集的基础数据包括年龄、品种、体重、血清生化浓度以及猫是否接受镇静或吸入麻醉进行尿道置管。采用单变量逻辑回归比较吸入麻醉和镇静。
在接受吸入麻醉与镇静的尿道梗阻猫中,并发症或梗阻复发无统计学差异。所有血清生化浓度均与生存率显著相关。血清离子钙降低与更高的并发症发生率( = 0.0086)和短期梗阻复发( = 0.004)显著相关。血清钾浓度升高与短期复发性尿道梗阻的风险显著相关( = 0.0345)。抗痉挛药物的使用与短期复发之间无显著差异。
在比较吸入麻醉与镇静方案时,并发症或复发率无显著差异。基础血清生化数据与并发症、生存率和短期复发率显著相关。