Schachner Lawrence, Alexis Andrew, Andriessen Anneke, Baldwin Hilary, Cork Michael, Kirsner Robert, Woolery-Lloyd Heather
J Drugs Dermatol. 2023 Feb 1;22(2):SF344607s3-SF344607s14.
Inflammatory skin disorders compromise skin barrier health. Early and daily skincare use aims to maintain a life-long healthy skin barrier. Racial/ethnic and age variations in skin barrier properties, cultural differences, and clinical presentation of the inflammatory skin disorder influence the choice of treatment and skin care. Ceramide-containing skin care may play a role in restoring and maintaining a healthy skin barrier.
A panel of 6 dermatologists met to develop consensus statements based on their 8 previous publications on promoting skin barrier health throughout life using ceramide-containing skin care. The publications covered skin barrier integrity in the newborn and infant, and the role of the skin barrier in mitigating atopic dermatitis (AD); racial/ethnic variations in the skin barrier and implications for skin care; the role of the skin barrier in inflammatory skin conditions including acne, AD and psoriasis in skin of color (SOC) populations; skin barrier integrity in patients with rosacea; and xerosis in patients with diabetes mellitus. The panel synthesized the 8 publications, selected information from a literature review, and their expert opinions and experiences to create the statements. The consensus was reached through a modified Delphi method where the panel met face-to-face and followed up virtually.
The panel adopted 6 consensus statements highlighting the importance of skin care in restoring/maintaining a healthy skin barrier in the populations mentioned above. Skin care suited to this role is gentle, has near-physiologic pH, is pleasant to use, and contains ceramides. This type of skin care can promote a healthy skin barrier and attenuate or delay inflammatory skin conditions.
Adjunctive daily skin care throughout life promotes a healthy skin barrier and is beneficial in managing various inflammatory skin disorders in all populations. However, when choosing optimal treatment and skin care, physicians should consider variations in age, skin properties, presentation of the condition, and cultural differences. J Drugs Dermatol. 2023;22:2(Suppl 1):s3-14.
炎症性皮肤病会损害皮肤屏障健康。早期和日常使用护肤品旨在维持终身健康的皮肤屏障。皮肤屏障特性的种族/民族和年龄差异、文化差异以及炎症性皮肤病的临床表现会影响治疗和皮肤护理的选择。含神经酰胺的护肤品可能在恢复和维持健康的皮肤屏障方面发挥作用。
由6名皮肤科医生组成的小组会面，根据他们之前发表的8篇关于使用含神经酰胺的护肤品促进终身皮肤屏障健康的文章制定共识声明。这些文章涵盖了新生儿和婴儿的皮肤屏障完整性，以及皮肤屏障在减轻特应性皮炎（AD）中的作用；皮肤屏障的种族/民族差异及其对皮肤护理的影响；皮肤屏障在包括痤疮、AD和银屑病在内的炎症性皮肤病在有色人种（SOC）人群皮肤中的作用；酒渣鼻患者的皮肤屏障完整性；以及糖尿病患者的皮肤干燥。该小组综合了这8篇文章，并从文献综述中选取信息，结合他们的专家意见和经验来制定声明。通过一种改良的德尔菲法达成共识，即小组成员面对面开会，并进行线上跟进。
该小组通过了6条共识声明,强调了皮肤护理在恢复/维持上述人群健康皮肤屏障方面的重要性。适合此作用的皮肤护理产品温和，pH值接近生理值，使用起来令人愉悦，并且含有神经酰胺。这种类型的皮肤护理可以促进健康的皮肤屏障，并减轻或延缓炎症性皮肤病。
终身辅助性日常皮肤护理可促进健康的皮肤屏障，对管理所有人群的各种炎症性皮肤病有益。然而，在选择最佳治疗方法和皮肤护理时，医生应考虑年龄、皮肤特性、病情表现和文化差异。《药物皮肤病学杂志》。2023；22：2（增刊1）：s3 - 14。
