Fayol V, Cloppet H, Hartmann D J, Ville G
Centre de Radio-analyse, Institut Pasteur, Lyon.
Ann Biol Clin (Paris). 1987;45(4):409-11.
Serum immunoglobulin levels IgG, IgA, IgM were assayed by laser-nephelometry and IgD by a liquid phase radio-immunoassay in 133 patients with monoclonal gammopathy. Our result show that IgD concentration decrease in parallel with polyclonal immunoglobulin levels. We observe a decrease of IgD level, more pronounced in malignant gammopathy in which the polyclonal immunoglobulin levels are usually low.
采用激光散射比浊法检测了133例单克隆丙种球蛋白病患者的血清免疫球蛋白水平IgG、IgA、IgM,采用液相放射免疫分析法检测了IgD。我们的结果显示,IgD浓度与多克隆免疫球蛋白水平呈平行下降。我们观察到IgD水平下降,在恶性丙种球蛋白病中更为明显,其中多克隆免疫球蛋白水平通常较低。