Friedman L N, Sullivan G M, Bevilaqua R P, Loscos R
HS Systems, Inc., New York, New York.
Am Rev Respir Dis. 1987 Nov;136(5):1188-92. doi: 10.1164/ajrccm/136.5.1188.
To ascertain the value of screening for tuberculosis in the New York City (NYC) alcoholic and drug abusing welfare population, 2,641 clients were interviewed, and 970 (36.7%) of them met preestablished criteria for alcohol or drug abuse. The prevalence of active tuberculosis was 0.91%, which is 28 times the age-matched NYC rate. Screening only those persons with a positive PPD and a cough substantially increased the yield of active tuberculosis to 7.2%, or 225 times the NYC rate. The prevalence of a positive tuberculin skin test was 32.4%, or 1.5 times greater than the age-matched NYC rate. Treatment or prophylaxis for tuberculosis was required in 128 or 13.2% of the screened population. Seventy thousand NYC welfare clients are routinely evaluated for medical illness each year. This study predicts that in 1 yr this subpopulation could yield 239 clients with active tuberculosis and 3,181 requiring INH prophylaxis. Screening for tuberculosis in the alcoholic and drug abusing welfare clients is therefore urgently recommended.
为确定在纽约市酗酒和滥用药物的福利人群中进行结核病筛查的价值,对2641名服务对象进行了访谈,其中970人(36.7%)符合酗酒或药物滥用的既定标准。活动性结核病的患病率为0.91%,是纽约市同年龄组患病率的28倍。仅对结核菌素试验(PPD)呈阳性且咳嗽的人进行筛查,活动性结核病的检出率大幅提高至7.2%,即纽约市患病率的225倍。结核菌素皮肤试验阳性的患病率为32.4%,比纽约市同年龄组患病率高1.5倍。在接受筛查的人群中,128人(13.2%)需要进行结核病治疗或预防。纽约市每年有7万名福利服务对象接受常规医疗评估。该研究预测,在1年时间里,这一亚人群可能会有239名活动性结核病患者以及3181人需要接受异烟肼预防治疗。因此,迫切建议对酗酒和滥用药物的福利服务对象进行结核病筛查。