Rose D F, Sato S, Smith P D, Porter R J, Theodore W H, Friauf W, Bonner R, Jabbari B
Medical Neurology Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.
Ann Neurol. 1987 Sep;22(3):348-54. doi: 10.1002/ana.410220311.
Three young adults with intractable complex partial seizures were studied by electroencephalography, magnetoencephalography, and electrocorticography. Interictal electroencephalographic (EEG) spikes for each patient were grouped according to their morphological characteristics and distribution across channels. Mapping of simultaneously recorded magnetoencephalographic signals produced dipolar patterns from which the three-dimensional locations of equivalent current dipoles were calculated, whereas the mapping of EEG spikes showed single regions of electronegativity. The magnetic spikes were localized to the anterotemporal lobe, and the EEG spikes were localized somewhat anterior or posterior to the magnetic spikes. The magnetoencephalographic findings corresponded well with intraoperative electrocorticographic and depth-electrode findings of discharging areas located over the lateral temporal lobe and on the basal and mesial surfaces of the temporal cortex.
对三名患有顽固性复杂部分性癫痫的年轻人进行了脑电图、脑磁图和皮质脑电图研究。根据每个患者发作间期脑电图（EEG）尖波的形态特征和跨通道分布进行分组。同步记录的脑磁图信号映射产生偶极模式，据此计算等效电流偶极的三维位置，而脑电图尖波映射显示单一的电负性区域。磁尖波定位于前颞叶，而脑电图尖波定位于磁尖波稍前或稍后的位置。脑磁图结果与术中皮质脑电图及深部电极在颞叶外侧以及颞叶皮质基底面和内侧面放电区域的结果非常吻合。
