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中性粒细胞-淋巴细胞和血小板-淋巴细胞比值对颞下颌关节强直术后复发的预测作用。

The predictive effect of neutrophil-lymphocyte and platelet-lymphocyte ratios in the post-operative recurrence of temporomandibular joint ankylosis.

机构信息

Department of Plastic Reconstructive and Aesthetic Surgery, İstanbul University İstanbul Faculty of Medicine, İstanbul-Türkiye.

出版信息

Ulus Travma Acil Cerrahi Derg. 2023 Feb;29(2):224-229. doi: 10.14744/tjtes.2023.01801.

Abstract

BACKGROUND

Reankylosis is a frequent pathology in patients who are operated for post-traumatic temporomandibular joint (TMJ) ankylosis. In the current practice, ankylosing spondylitis attacks are monitored with the increases in neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR). In this study, such a relation between TMJ reankylosis and increase in these ratios was evaluated.

METHODS

Patients who were operated between January 2010 and December 2019 for unilateral or bilateral TMJ ankylosis were included in this study. Temporomandibular gap arthroplasty with an interpositional silicone block was performed for each patient by the same operative team. Each patient had standard physiotherapy. All ages and genders were included in the study. Due to the complete blood count differences between children and adults, 18 years of age was used as a cutoff between the groups. A need for reoperation was accepted as reankylosis. The NLR and PLR of children without and with reankylosis and adults without and with reankylosis were compared.

RESULTS

Twenty-nine children and 38 adults were included in the study. Mean age of the children and adults were 10.8 and 37.3 years, respectively. Eleven children and eight adults had reankylosis. In patients with reankylosis, NLR and PLR were high significantly, regardless of age. In children, PLR was significantly higher in reankylosis patients. In adults, NLR was significantly higher in reankylosis patients.

CONCLUSION

PLR and NLR may be utilized for predicting reankylosis, respectively, in children and adults who were operated for ankylosis due to TMJ fractures.

摘要

背景

创伤性颞下颌关节(TMJ)强直术后患者常发生再强直。目前,强直性脊柱炎的治疗主要通过中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)的升高来监测。本研究旨在评估 TMJ 再强直与这些比值升高之间的关系。

方法

本研究纳入了 2010 年 1 月至 2019 年 12 月间因单侧或双侧 TMJ 强直而接受手术的患者。由同一手术团队为每位患者行 TMJ 关节切开松解术并植入硅橡胶间隔物。每位患者均接受标准的物理治疗。本研究纳入所有年龄和性别患者。由于儿童和成人的全血细胞计数存在差异,本研究以 18 岁为界将患者分为两组。将需要再次手术定义为再强直。比较了无再强直的儿童和成人以及有再强直的儿童和成人的 NLR 和 PLR。

结果

本研究共纳入 29 名儿童和 38 名成人。儿童和成人的平均年龄分别为 10.8 岁和 37.3 岁。11 名儿童和 8 名成人发生再强直。无论年龄大小,有再强直的患者 NLR 和 PLR 均显著升高。在儿童中,有再强直的患者 PLR 显著升高。在成人中,有再强直的患者 NLR 显著升高。

结论

PLR 和 NLR 可能分别用于预测因 TMJ 骨折导致强直而接受手术的儿童和成人的再强直。

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本文引用的文献

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Reducing macrophage numbers alleviates temporomandibular joint ankylosis.减少巨噬细胞数量可缓解颞下颌关节强直。
Cell Tissue Res. 2020 Mar;379(3):521-536. doi: 10.1007/s00441-019-03087-7. Epub 2019 Sep 14.
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Recurrence-Related Factors of Temporomandibular Joint Ankylosis: A 10-Year Experience.颞下颌关节强直的复发相关因素:十年经验
J Oral Maxillofac Surg. 2019 Dec;77(12):2512-2521. doi: 10.1016/j.joms.2019.06.172. Epub 2019 Jul 2.
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Ankylosis of the Temporomandibular Joint in Pediatric Patients.小儿颞下颌关节强直
J Craniofac Surg. 2019 Jun;30(4):1033-1038. doi: 10.1097/SCS.0000000000005547.

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