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来自 Maxim. 的青核桃壳中的两种新二芳基庚烷类化合物。

Two new diarylheptanoids from the green walnut husks of Maxim.

作者信息

Zhou Yuan-Yuan, Liu Ning-Yu, Zhang Xiao-Juan, Sun Yan-Ping, Liu Yan, Fu Qi-Feng, Yang Bing-You, Kuang Hai-Xue

机构信息

Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin, China.

Academic Research Department, Heilongjiang University of Chinese Medicine, Harbin, China.

出版信息

Nat Prod Res. 2024 Jul;38(13):2237-2244. doi: 10.1080/14786419.2023.2169918. Epub 2023 Feb 7.

Abstract

Chemical investigation on the 95% ethanol extract of green walnut husks of Maxim. led to the isolation of two new diarylheptanoid compounds, including Juglanin K () and Myricananin I (), together with ten known compounds (). Their structures were elucidated by extensive analyses of comprehensive spectroscopic methods. The isolated compounds were evaluated for their antibacterial activities against and . The results showed that compound had moderate antibacterial activity with the MIC values of 0.313 and 0.156 mg/mL, respectively. compounds , - and showed weakly antibacterial activities against and with the MIC values of 0.625-2.5 mg/mL.

摘要

对胡桃楸青胡桃壳95%乙醇提取物进行的化学研究。从中分离出两种新的二芳基庚烷类化合物,包括胡桃素K()和杨梅黄素I(),以及十种已知化合物()。通过综合光谱方法的广泛分析阐明了它们的结构。对分离出的化合物进行了针对和的抗菌活性评估。结果表明,化合物具有中等抗菌活性,其MIC值分别为0.313和0.156毫克/毫升。化合物、 - 和对和表现出弱抗菌活性,MIC值为0.625 - 2.5毫克/毫升。

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