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对有β-内酰胺类过敏的妊娠患者的管理。

Management of the Pregnant Patient with Beta-Lactam Allergy.

作者信息

Wolfson Anna R, Schatz Michael X

机构信息

Harvard Medical School, Boston, MA, USA.

Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

出版信息

Curr Allergy Asthma Rep. 2023 Mar;23(3):189-194. doi: 10.1007/s11882-023-01069-y. Epub 2023 Feb 7.

Abstract

PURPOSE OF REVIEW

We review the literature and discuss the logistics of testing pregnant patients for penicillin allergy.

RECENT FINDINGS

As in the general population, pregnant patients commonly report a penicillin allergy, but most patients are able to tolerate penicillin. Avoidance of beta-lactams in pregnancy is associated with increased morbidity: longer hospitalizations, more frequent infections, and more complications. Penicillin allergy testing is safe in pregnant patients, and obstetricians are eager for allergists to offer this procedure to their patients. As allergists, we can improve our patients' health outcomes by offering penicillin allergy testing in our practices. The protocols for testing both with and without skin testing in pregnant patients have been studied, and future studies will continue to clarify the safety and efficacy of penicillin allergy delabeling in pregnant patients.

摘要

综述目的

我们回顾了相关文献,并讨论了对孕妇进行青霉素过敏检测的相关事宜。

最新发现

与普通人群一样,孕妇常报告有青霉素过敏,但大多数患者能够耐受青霉素。孕期避免使用β-内酰胺类药物会增加发病率,如住院时间延长、感染更频繁以及并发症更多。青霉素过敏检测对孕妇是安全的,产科医生渴望过敏症专科医生为他们的患者提供此项检测。作为过敏症专科医生,我们可以通过在临床实践中提供青霉素过敏检测来改善患者的健康状况。已经对孕妇进行有或无皮肤试验的检测方案进行了研究,未来的研究将继续阐明孕妇青霉素过敏标签去除的安全性和有效性。

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